Microbio Final Test Questions – Flashcards

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4 Types of Infections of the Blood
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1. fungamia

2. bacteremia

3.viremia

4.parasitemia

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Pathogenic organism growing in the blood can lead to?
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sepsis & septic shock
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What can also be caused by pathogens growing inside or outside of intravenous devices?
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bacteremia and fungemia
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What complications can arise from infectious endocarditis?
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1. risk of congestive heart failure 

2. rupture the chordae tendinae

3. kidney damage (blood in urine)

4. perforation of the valves 

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What can be the cause of sepsis and septic shock?
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1. gram+ bacteria

2. gram- bacteria

3.fungi

4.protozoa

5.viruses

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Bacterial Infections of the blood?
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1. plague: yersinia pestis

2. brucellosis: brucella 

3. lyme disease: borrelia burgdorferi

 

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Rickettsial infections of the blood?
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1. Rocky Mountain Spotted Fever: rickettsia rickettsii

2. Epidemic typhus: rickettsia prowazekii

3. Endemic typhus: rickettsia typhi

 

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Viral Infections of the blood?
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1. cytomegalovirus

2. arboviruses

3. epstein-barr virus

4. filovirus (ebola & marburg)

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The plage is caused by what bacteria?
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yersinia pestis
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How is the plague transmitted?
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vector
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How does the plague spread?
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from lymph nodes to blood (from there possibly to lungs)
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Brucellosis is caused by what bacteria?
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brucella
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what kind of infection is brucellosis?
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zoonotic infection
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what part of the body does brucellosis affect?
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reproductive tract
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how does brucellosis enter the body?
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1.through cuts in the skin

2. contact with mucous membrane

3. inhalation

4. ingestion

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is brucellosis a chronic or acute illness?
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chronic
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how long can brucellosis last?
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for weeks or months
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what does brucellosis cause?
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1. fever

2. night sweats

3. weight loss

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what is lyme disease transmitted by?
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ixodes ticks
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what is lyme disease caused by?
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borrelia burgdofefi
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is borrelia burgdorferi gram negative or gram positive?
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gram negative
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what disease does borrelia bugdorferi cause?
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lyme disease
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what animals does borrelia burgdorferi involve?
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1. ticks

2. mice

3. deer

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Acute lyme disease can be characterized by?
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1. fever

2. migratory bulls-ey rash

3. muscular joint pain

4. often meningeal irritation

 

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true or false do rickettsia have characteristics of both bacteria and viruses?
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true
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rickettsia are what shape?
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coccobacilli
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how do rickettsia divide?
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binary fusion
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what is the most common rickettsial infection?
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rocky mountain spotted fever
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rocky mountain spotted fever is caused by bacteria?
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rickettsia rickettsii
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what is epidemic typhus characterized by?
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1. fever

2. rash

3. muscle aches

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what is epidemic typhus caused by?
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rickettsia prowazekii
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what is endemic typhus caused by?
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rickettsia typhi
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primary infection of endemic typhus is?
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rodent to rodent
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what are some symptoms of endemic typhus?
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1. headache

2. muscle aches

3. fever

4. maculopapular rash forms

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cytomegalovirus is?
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a herpes viral genus of the herpesvirus group
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arboviruses are?
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a group of viruses that are transmitted by arthropod vectors 
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arboviruses infections in the blood are classified as?
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fever infections
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dengue and yellow fever are both what type of virus?
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arbovirus
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what do dengue and yellow fever attack?
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the liver
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the epstein-barr virus is?
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human herpes virus
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ebola and marburg are both what type of viruses?
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filoviruses
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true or false ebola virus is very contagious?
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true
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what is marburg virus mortality rate?
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25%
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what causes hemorrhaging in the skin, mucous membranes, and internal organs
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ebola and marburg virus
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Gas gangrene is caused by what bacteria?
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clostridium pefringens
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the CNS consists of the?
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brain and the spinal cord
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CNS infections can be caused by?
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1. normal bacterial flora

2. pathogens acquired through ngestion

3. pathogens acquired during the birthing process

4. contamination of shunts

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Purulent meningitis is?
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infection of the meninges 
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Purulent meningitis is characterized by?
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1. fever

2. irritability

3. various degress of neurological dysfunction

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Chronic meningitis is usually caused by?
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mycobacterium tuberculosis

fungi

or protozoan parasites 

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chronic meningitis is characterized by?
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fever

headache

stiff neck and back

nausea

vomiting 

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Ecephalitis
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involves seizures, paralysis, or defective mental faculties 
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Poliomyelitis is ?
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infection which destroys cells associated with the anterior portion of the spinal cord and brain stem
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what does poliomyelitis cause?
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weakness or paralysis of muscle groups

respiratory difficulties

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poliomyelitis is characterized by?
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asymmetrical paralysis
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acute poliomyelitis is?
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inflammatory infection of the peripheral nervous system 
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peripheral nervous system consists of?
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nerves and ganglia outside of the brain and the spinal cord
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acute poliomyelitis is characterized by?
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symmetrical paralysis
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acute poliomyelitis can be caused by?
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1. diphtheria toxin

2. enteric pahtogens

3. cytomegalovirus

4. esptein-barr virus 

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acute meningitis usually caused by?
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h. influenzae

n. meningitidis

s. pneumoniae

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a vaccine is available to protect against h. influenzae (acute meningitis)
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yes
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what bacteria are often involved in meningitis in newborns?
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group b streptococci and e.coli
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what are the common pathogens of the CNS?
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1.  Purulent meningitis

2. chronic meningitis

3. encephalitis

4. poliomyelitis 

5. tetanus: colstridium tetani

6. botulism: clostridium botulinum 

7. acute poliomyelitis 

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most common viral causes of acute CNS infections?
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enterovirus

herpes simplex virus

HIV

Epstein- Barr virus

also several arthropod viruses

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tetanus is caused by?
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clostridium tetani
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botulism is caused by?
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clostridium botulinum
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clostridium botulinum is found naturally in?
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soil and sediments of ponds and lakes 
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What are rabies?
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an acute and fatal viral CNS infection
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what is the mortality rate for rabies?
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90%
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polio is what kind of virus?
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enterovirus
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Bovine Spongiform Encephalopathy is also called
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mad cow disease
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when was BSE first identified?
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1986
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BSE infection in humans is called what?
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Creutzfeld-Jacod disease (vCJD)
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what is the most important fungal CNS infection
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cryptococcosis
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cryptococcosis is caused by?
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cryptococcus neoformans
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