Inhibition agents – Flashcards
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B- lactam drug |
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pcn and cepholasporin - inbibit peptie bridge forming
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Vancomycin |
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inhibits formation of gylcan chains by preventing fomation of pTG and cell wall - treats infections cuased by pcn rsistnant gram+ - nyst be given intravenously |
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Bacitracin |
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interferes w transport of PTG precursos across CPMem. topical |
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Aminoglycosides |
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irreversibly 30S rib - not affective against anerobes, entercocci, streptococci
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tetracyclines |
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reversibly 30S rib -effective on some gram +/- - long hald life--- less freq. dose
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macrolides |
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reversibly 50S gram + and atypical pneumonia
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choloramphenicol |
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50S last resort for life threatening aplastic anemia |
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lincosamides |
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inhibits gram +/- treats infection from intestinal perforation clinamycin |
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Fluroquinoles |
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inhibit action of DNA gyrase |