fungal mycoses – Flashcards
Unlock all answers in this set
Unlock answersquestion
Which fungal infections are characterized by a splendore hoeppli asteroid body? |
answer
sporotrichosis, coccioidomycoses, aspergillosis, candidiasis, mycetoma |
question
What subcutaneous mycosis can also present as plaques? |
answer
phaeohyphomycoses |
question
What type of fungi is likely to cause systemic mycosis? |
answer
Thermally dimorphic fungi, among others |
question
Where is blastomyces usually found (in environment)? |
answer
Dead/decaying organic matter/leaf litter |
question
What is the only yeast w/ broad based buds? |
answer
blastomyces |
question
Does blastomyces spread person-person? |
answer
NOOOOOOO!!!!!! thermal dimorphs usually don't - they're often in a granuloma and not terribly transmissible |
question
Blastomycosis symptoms? |
answer
1ary: flu-like, with patchy lobar infiltrates chronic: TB-like 2ary: systemic-> liver, spleen, prostate, UG, brain |
question
Which of the coccidioides is found only in Cali? |
answer
C. immitis |
question
Which fungi is characterized by spherules filled with endospores? |
answer
Coccidioides |
question
What environments are associated with h. capsulatum? |
answer
Bird/bat guano enriched soils, old buildings, bird roosts, caves |
question
What are symptoms of disseminated histoplasmosis? |
answer
Weight loss, fatigue, oropharyngeal ulcers, hepatosplenomegaly, bone marrow lesions, adrenal insufficiency, meningitis: REALLY SERIOUS, though acute histoplasmosis is self-limiting + flu-like |
question
Which h. capsulatum should you use serum tests to diagnose? Culture? |
answer
For non-disseminated, use serum; for invasive, use culture |
question
Which thermally dimorphic yeast will you always find intracellularly in the yeast form? |
answer
H. capsulatum |
question
What is the only intracellular thermal dimorph? |
answer
H. capsulatum |
question
What is the main thermal dimorph of s. america? |
answer
Parracoccidioides |
question
Which fungi are resistant to voricanazole? |
answer
Zygomycota (mucor, rhizopus), Sporothrix schenckii, paracoccidioides, Candida glabrata, cryptococcus |
question
Candida transmission? |
answer
Part of normal flora - endogenous infection (overgrowth of flora -> infection) possible. Also exogenous, either from contaminated object or from a person. |
question
What is the most common infective Candida sp.? |
answer
C. albicans |
question
What is the most common disease involving the CNS? |
answer
Cryptococcus |
question
What sort of soil is particularly likely to harbor cryptococcus? |
answer
Enriched by pigeon droppings |
question
What are 3 characteristics of cryptococcus that distinguishes it from other yeasts? |
answer
1) melanin production (-> birdseed/niger) 2) variable size 3) capsule |
question
What is a particularly angioinvasive opportunistic fungus? |
answer
zygomycosas |
question
What is the most common opportunistic pathogen of AIDS patients with low CD4? |
answer
Pneumocystis |
question
What are characteristic morphologies of pneumocystis? |
answer
cysts, trophozoites, sporocysts - NO BUDDING (cannot be cultured) |