Famotidine ~ Pepcid

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Generic:
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FAMOTIDINE
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Brand:
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Pepcid, Pepcid AC
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Classifications:
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gastrointestinal agent; antisecretory agent (h2-receptor antagonist)
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Pregnancy Category:
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B
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Availability:
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10 mg, 20 mg, 40 mg tablets; 40 mg/5 mL suspension; 10 mg/mL, 20 mg/50 mL injection
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Contraindications:
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Safe use during pregnancy (category B), by nursing mothers
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Cautious Use:
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Renal insufficiency.
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Route & Dosage:
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Duodenal Ulcer, Adult: PO 40 mg h.s. or 20 mg b.i.d. PO Maintenance Therapy 20 mg h.s. IV 20 mg q12h. Pathological Hypersecretory Conditions, Adult: PO 20-160 mg q6h. GERD, Gastritis, Adult: PO 10 mg b.i.d. Renal Impairment, Clcr <50 mL/min: 50% of usual dose or usual dose q36-48h for all indications
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Adverse Effects: CNS:
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Dizziness, headache, confusion, depression.
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Adverse Effects: GI:
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Constipation, diarrhea.
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Adverse Effects: Skin:
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Rash, acne, pruritus, dry skin, flushing.
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Adverse Effects: Hematologic:
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Thrombocytopenia.
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Adverse Effects: Urogenital:
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Increases in BUN and serum creatinine
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Nursing Implications:
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Monitor for improvement in GI distress. Monitor for signs of GI bleeding
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Patient Education:
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Be aware that pain relief may not be experienced for several days after starting therapy. Do not breast feed while taking this drug without consulting physician

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