Psychology Ch 13: Biology of learning and Memory – Flashcards
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Altered tau protein cannot bind to its usual targets within axons, and so it
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starts spreading into the cell body and dendrites
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What is a major advantage of Aplysia for studies on the physiology of learning?
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There is great similarity of nervous system anatomy from one individual to another.
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Lashley trained rats on a variety of mazes, then made deep cuts in their cortexes. He found that the cuts produced:
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Little apparent affect
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How does one produce long-term potentiation of cells in the mammalian nervous system?
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a burst of many stimuli within a few seconds
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Following a certain kind of experience in Aplysia, a facilitating interneuron causes changes that block the potassium channels at the end of the axon of the sensory neuron, leading to:
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Sensitization
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It is believed that Hebbian synapses may be critical for:
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Associative learning
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In Aplysia, sensitization has been found to depend on a series of events that:
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block potassium channels in the sensory neuron.
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Nearly simultaneous stimulation by two or more axons produces LTP, whereas stimulation by just one produces it weakly, if at all. This is known as the property of:
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Cooperativity
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Research on Aplysia shows us that at least one physiological basis for learning involves which of the following?
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increased dendrite branching
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In Pavlov's experiments, he presented a sound followed by meat. Gradually the sound came to elicit salivation. The salivation to the meat in this experiment was the:
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Condition response
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Operant conditioning is to ____ as classical conditioning is to ____.
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Consequence; association
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The cortex works as a whole, and the more cortex the better, defines:
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Mass action
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A distinctive symptom of Korsakoff's syndrome is:
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confabulation
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Most Korsakoff's victims have a loss or shrinkage of neurons throughout the brain, especially in the:
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dorsomedial thalamus.
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Blocking NMDA synapses has what effect, if any, on LTP?
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It prevents the establishment of LTP.
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The general function of working memory is to:
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Attend to and operate on current information.
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When glutamate massively stimulates AMPA receptors, the resulting depolarization:
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Enables glutamate to stimulate nearby NMDA receptors.
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Restlessness, depression, hallucinations and loss of appetite all accompany:
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Alzheimer's disease.
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The delayed response task requires responding to something that you saw or heard ____.
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a short while ago
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Lashley found that a deep cut in a rat's cerebral cortex completely eliminated the effects of learning under what circumstances, if any?
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under none of the circumstances he studied
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"All parts of the cortex contribute equally to complex behaviors such as learning" defines
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equipotentiality.
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Why did some experimenters in the 1960's and 1970's grind up the brains of some rats and inject extracts into other rats?
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It was believed that memories could be transferred in this way.
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Amyloid is to ____, as tau is to ____.
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plaques, tangles
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A diet low in calcium could possible interfere with learning by preventing:
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activation of CaMKII.
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In some cases of Alzheimer's disease that run in families, the cause of the disease appears to involve which gene(s)?
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genes on several different chromosomes
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Researchers have found several drugs, including ____, which weaken memories of recent events.
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Propranolol
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Habituation of the gill withdrawal response in Aplysia depends on:
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a change in the synapse between the sensory neuron and the motor neuron.
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Lashley's conclusions from his engram research were based on certain unnecessary assumptions, which later psychologists have discarded. One of those assumptions was that the:
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brain treats all kinds of memory the same way.
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Strong stimulation anywhere on the skin of an Aplysia excites axons that attach to receptors and:
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close potassium channels in the membrane.
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What is a major advantage of Aplysia for studies on the physiology of learning?
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There is great similarity of nervous system anatomy from one individual to another.
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The most likely cause of the brain damage typical of Alzheimer's disease is due to a:
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increase in amyloid-β proteins.
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Researchers begin to look for clues to the genetics of Alzheimer's by investigating the chromosome related to:
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Down syndrome.
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What is the current status of research on transfer of training through brain extracts?
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Research ended without a conclusion because the phenomenon was difficult to replicate.
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In studies that paired a tone with an air puff to the cornea of rabbits, learning was found to depend on one nucleus of the:
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cerebellum.
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Giving a dolphin a treat when it does a summersault would be considered a(n):
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reinforcement.
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While studying classical conditioning of the eyelid response in rabbits, investigators suppress the activity of the red nucleus. What results will occur?
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Learning will not occur.
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Damage to the ____ produces symptoms similar to Korsakoff's syndrome.
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prefrontal cortex
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Donald Hebb (1949) distinguished between two types of memory that he called
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short-term and long-term.
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The NMDA receptor responds to its transmitters when:
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the membrane is already at least partly depolarized.
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Which of the following experiments would be a reasonable test of whether an animal has suffered damage to its hippocampus?
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Does it reenter a single arm before entering all the other appropriate arms in a radial maze?
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The study of amnesic patients leads us to the conclusion that people have ____ kind of memory, and that memory depends on ____ of the brain.
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more than one; different parts
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In Pavlov's experiments, he presented a sound followed by meat. Gradually the sound came to elicit salivation. The salivation to the meat in this experiment was the:
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unconditioned response.
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Pavlov believed that classical conditioning reflected a strengthened connection between two brain areas that were activated by:
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the CS and UCS.
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People with parietal lobe damage the process of ____ is damaged.
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associating one event with another
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Structures formed from degenerating neuronal cell bodies are called:
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tangles.
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Researchers have found that different species of birds differ in terms of how much they depend on food they have stored to get through the winter. What factor is related to depending on and finding stored food?
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relative size of the hippocampus
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How does one produce long-term potentiation of cells in the mammalian nervous system?
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a burst of many stimuli within a few seconds
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What type of deficiency causes Korsakoff's syndrome?
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Thiamine
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H.M. was able to learn and remember:
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skills like mazes and puzzles.
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____ is an influence of recent experience on behavior, even if one does not recognize that influence.
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Implicit memory
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The ability to state a memory in words is termed:
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declarative memory.
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Short-term memory may be characterized as:
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having a limited capacity.
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Lashley trained rats on a variety of mazes, then made deep cuts in their cortexes. He found that the cuts produced:
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little apparent effect.
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Forgetting events prior to the time of brain damage is a characteristic of ____ amnesia.
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retrograde
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A possible treatment for Alzheimer's is the administration of drugs that:
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stimulate acetylcholine receptors.
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Most researchers now believe that the accumulation of amyloid and tau protein:
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are partly the cause of Alzheimer's disease.
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conditioning that pairs a neutral stimulus with a stimulus that evokes a reflex
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classical conditioning
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a type of learning in which behavior is strengthened if followed by a reinforcer or diminished if followed by a punisher.
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operant conditioning
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an event that decreases the behavior that it follows
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punishment
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(psychology) a stimulus that strengthens or weakens the behavior that produced it
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reinforcement
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the physical representation of what has been learned. a connection between two brain areas would be a possiblility of one.
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engram
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all parts of the cortex contributeequally to the complex behaviors such as learning; any part of the cortex can substitue for any other
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equipotentiality
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The cortex works as a whole, and the more cortex the better (principle Karl Lashley proposed).
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mass action
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The memory stage with a small capacity (7 +- 2 chunks) and brief duration (< 30 seconds) that we are consciously aware of and in which we do our problem solving, reasoning and decision making.
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short term memory
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the relatively permanent and limitless storehouse of the memory system. Includes knowledge, skills, and experiences
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long term memory
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Temporarily holds current or recent information for immediate or short-term use; Information is maintained for 20-30 seconds while active processing (e.g., rehearsal) takes place
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working memory
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loss of memory
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amnesia
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a loss of memory for events prior to a brain injury
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retrograde amnesia
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a loss of memory for any event that occurs after a brain injury
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anterograde amnesia
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the unintentional influence of prior experiences
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implicit memory
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Memory that has been processed with attention and can be consciously recalled
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explicit memory
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the ability to state a memory in words
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declarative memory
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memory of how to do things that require motor or performance skills
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procedural memory
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a subject must navigate through a maze with 8 or more radial arms with a reward at the end
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radial maze
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Animal must find hidden platform using spatial cues in the room (relative positions of objects)
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morris water maze
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to unite; to strengthen; to make solid or firmly established
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consolidated
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memory disorder related to thiamine deficiency generaly associated with chronic alcoholism; fail to recall many items or events of the past
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korsakoff's syndrome
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the act of filling in memory with statements that make sense but that are,in fact un-true
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confabulation
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an irreversible, progressive brain disorder, characterized by the deterioration of memory, language, and eventually, physical functioning
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alzheimer's disease
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a condition of retardation and associated physical disorders caused by an extra chromosome in one's genetic makeup
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down syndrome
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brain cell clumps seen in Alzheimer's disease and caused by the buildup of amyloid protein.
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plaques
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Tau produces these, structures formed from degenerating structures within neuronal cell bodies
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tangles
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A synapse that increases in effectiveness because of simultaneous activity in the presynaptic & postsynaptic neurons is called this
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hebbian synapse
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decreasing responsiveness with repeated stimulation
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habituation
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(psychology) the process of becoming highly sensitive to specific events or situations (especially emotional events or situations)
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sensitization
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an increase in a synapse's firing potential after brief, rapid stimulation. believed to be a neural basis for learning and memory
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long term potentiation
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long term decrease in the excitability of a neuron caused by stimulation of the terminal button while the postsynaptic membrane is hyperpolarized or only slightly deplorized
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long term depression
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a neurotransmitter that diffuses from the post-synaptic neuron back to the presynaptic neuron
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retrograde neurotransmitter