Chapter: Enzymes and Kinetics Mastering Chem – Flashcards

Arrange the events for the hydrolysis of amide bonds by chymotrypsin in their correct order. 1) attack by Ser 195 to give a tetrahedral intermediate 2) enzyme returns to initial state 3) protonation by His 57 and then cleavage of the C-N bond release the C-terminal fragment 4) protonation by His 57 and then cleavage of the C-O bond release the N-terminal fragment 5) attack by water, leading to formation of a tetrahedral intermediate 6) binding of substrate to properly position the scissile bond for cleavage

Enzymes can accelerate reactions by: 1)correctly positioning a metal ion for catalysis. 2)lowering the energy for activation. 3)binding a substrate or substrates. 4)promoting the removal or addition of protons. 5)all of the above.

In general, enzymes are what kinds of molecules?

Enzymes work by _____.

An enzyme _____.

What name is given to the reactants in an enzymatically catalyzed reaction?

As a result of its involvement in a reaction, an enzyme _____.