Chapter 40 – Nursing Care of Patients with Disorders of the Endocrine Pancreas – Flashcards

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Diabetes Mellitus
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Disorder of pancreas where beta cells of islets of langerhans fail to produce adquate amount of insulin -Disease in which high blood glucose results from defective insulin secretiono r action * Juvenile or insulin dependent (adult onset can be non-insulin dependent)
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endogenous
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derived or originating internally
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gastroparesis
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delayed gastric emptying
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glycosuria
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the presence of abnormally high levels of sugar in the urine
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hyperglycemia
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abnormally high blood sugar usually associated with diabetes
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hypoglycemia
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abnormally low blood sugar usually resulting from excessive insulin or a poor diet
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ketoacidosis
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acidosis with an accumulation of ketone bodies *Patient will have a sweet taste in the back of the mouth.
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Kussmaul's respirations
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increased rate and depth with panting and long grunting exhalation
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nephropathy
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a disease affecting the kidneys
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neuropathy
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any pathology of the peripheral nerves
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nocturia
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excessive urination at night
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polydipsia
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excessive thirst (as in cases of diabetes or kidney dysfunction)
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polyphagia
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excessive hunger
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polyuria
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renal disorder characterized by the production of large volumes of pale dilute urine
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postprandial
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following a meal (especially dinner)
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preprandial
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preceding a meal (especially dinner)
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retinopathy
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disease of the retina
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What should be included in the teaching for a 40 yr old with type 2-diabetes mellitus to prevent long term complications?
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1. Have regular eye examinations 2. Maintain good oral hygiene and make regular visits to the dentist 3. Wash, dry and inspect feet daily 4. Take daily aspirin as prescribed 5. See a podiatrist or other health care professional to monitor neuropathy
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Diabetes is diagnosed when the fasting plasma glucose drawn 8 hours without eating is?
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126 mg/dL or higher
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Which type of diabetes is most common?
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Type 2 Diabetes
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The nurse is caring for a patient with Type 1 diabetes mellitus being treated for pneumonia. Which lab value should the nurse monitor most closely to identify potential complications early?
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Urine Ketones
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A person with type 2 diabetes mellitus is scheduled for hip surgery and is upset because an infusion of glucose and insulin is being started; this is a change from the patients usual oral hypoglycemic therapy. What should the appropriate response from the nurse be?
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Surgery is a stressor that can alter blood glucose control and the IV medications are likely only temporary.
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The nurse is caring for a patient with Type 2 diabetes mellitus who started oral hypoglycemic medication 2 months ago for fasting blood glucose level of 160 mg/dl. What would be a good indicator that the treatment was working?
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HbA1c 5%
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What acute high blood glucose complication can occur as a result of uncontrolled type 2 DM?
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Hyperosmolar Hyperglycemia
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The nurse working on the endocrine unit is reviewing preprandial glucose results. Which results indicate the patients DM is well controlled?
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51yr old female with glucose = 115 mg/dL 29yr old male with glucose = 84 mg/dL
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The nurse is caring for a patient with type 2-DM who has taken an oral hypoglycemic agent who is now experiencing hunger, sweating, headache and agitation. which action should a nurse take first?
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Give 4oz of OJ
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The nurse is assisting with community education fair on risks for diabetes and heart disease. What are criteria for metabolic syndrome and should be included in instruction?
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Fasting plasma glucose = 100 mg/dL BP = 130/85 mm/Hg HDL cholesterol is <40 mg/dL for men and ,<50 mg/dL for woman
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What is a major cause of Type 1 diabetes?
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Destruction of beta cells in the Islets of Langerhans in the Pancreas
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Symptoms of uncontrolled DM
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Polydipsia, polyuria, polyphagia, glycosuria, nocturia, fatigue, blurred vision, abdominal pain, headache
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Treatment options for DM
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Nutrition, exercise, insulin or oral hypoglycemic agents, blood glucose monitoring, education
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Symptoms of Hypoglycemia
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Hunger sweating, tremor, blurred vision, headache and irritability; If not treated, confusion, seizures and coma
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Symptoms of diabetic neuropathy
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Numbness and pain in extremities, sexual dysfunction, gastroparesis
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Pathophysiology of type 2 DM
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Pancreas does not produce enough insulin or tissues are resistant to insulin, causing elevated blood glucose. heredity and obesity are major factors
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Criteria for metabolic or cardiometabolic syndrome
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Abdominal obesity, elevated triglycerides, decreased HDLs, BP >130/85 mm Hg, fasting plasma glucose (FPG) >110 mg/dL
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Acute, life threatening complication of uncontrolled type 2 diabetes
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Hyperosmolar hyperglycemia
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Nursing interventions to prevent amputation in DM
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Wash and dry feet daily in warm water, Apply non-alcohol-based lotion, Inspect for lesions daily, Wear cotton socks and leather shoes, Avoid crossing legs and wearing constricting clothing, Use care when cutting toenails, Have feet checked regularly by a health professional
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Causes of hypoglycemic episodes in diabetes
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Under-eating, skipping a meal, too much medication, too much exercise, poor timing of medication, food, exercise
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Steps for mixing insulins; Remember "clear to cloudy":
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-Assemble equipment -Check orders to conform type/dose of regular (clear) and intermediate acting (cloudy) insulins -Roll bottle of cloudy insulin -wipe tops of both bottles with alcohol -Draw up amount of air equal to dose of cloudy insulin 1. Inject air into cloudy vial, -Draw up amount of air equal to dose of clear insulin 2. Inject air into clear vial, 3. draw up clear insulin, have nurse double check 4. then draw up cloudy insulin, have nurse double check *If too much insulin drawn into syringe, discard and start over *Remember, never to mix insulin glargine (Lantus) *If the clear is drawn up last, the vial may be contaminated by the cloudy insulin, altering the action of the clear insulin *If the cloudy insulin is unknowingly contaminated by clear insulin, the clear will become cloudy and its effect will be diminished
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Mrs. Brown is a 52-year-old cook in a fast-food restaurant. She is 5'2" tall and weighs 190lbs. She says she is "shaped like a pumpkin" because her arms and legs are relatively thin compared to her middle. Because she tends to eat her meals at work, she has a high-fat, high-sodium diet that is low in fresh fruits and vegetables. She drinks diet soda all day long and spends long periods on her feet. Mrs Brown's sister has DM, but Mrs. Brown's blood glucose levels have always been normal whenever she has been tested.
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1. What factors place Mrs. Brown at risk for diabetes? Heredity Obesity Body shape Age 2. What actions can Mrs. Brown take to reduce her risk of developing diabetes? Lose weight Exercise regularly 3. Mrs. Brown tries to lose weight butis unsuccessful and, at age 57, is diagnosed with type 2 diabetes. Diabetes is diagnosed when the fasting plasma glucose is __________ mg/dL or greater? 126 mg/dL or greater for fasting plasma 200 mg/dL or greater for casual plasma with symptoms of diabetes are diagnostic for diabetes. 4. Mrs. brown develops a small blister on he bottom of her right heel. Which actions are important for her to take to make sure her heel heals? Gently wash, dry and inspect the area daily Use crutches to avoid bearing weight on the blister See podiatrist if it is not healed in 2-3 days *Wear shoes and socks for support *Never open blisters/wounds 5. Mrs. Brown is very disciplined. her foot heals, and she loses 50 lbs. Her physician tells her to stop her metformin (Glucophage) and return to the office for follow-up in 3 months. What blood test can the physician order that will reflect her blood glucose control over 3 months? Glycohemoglobin or HbA1c test reflects 2-3 months. Normal is 45-65. The American Diabetic Association recommends less than 7% as a goal for people with diabetes.
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Endogenous hormone
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Is made by the body and does not need to be ingested or injected
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Glycosuria results when...
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the kidneys are unable to reabsorb all the glucose in the renal tubules
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Diabetic ketoacidosis or ketoacidosis is an acute complication risk for persons with type 1 DM if...
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Blood glucose is uncontrolled and insulin is deficient
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Kussmaul's respirations are used to ....
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Eliminate excess acidity in patients with diabetic ketoacidosis
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Nephropathy
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Diabetic kidney disease
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Postprandial blood glucose tests are recommended to....
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Determine the response of blood glucose to a meal
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Retinopathy
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A microvascular disease caused by complication of DM
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4% - 6% is the normal level of...
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glycohemoglobin
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Believed to be caused by an auto immune response, what percentage of diabetic patients have Type 1 diabetes?
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5% - 10%
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Difference between Type 1 and Type 2 diabetes is...
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Type 1-Must have insulin because body is not producing it Type 2- Body not producing enough and body needs the glucose for energy
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Goal in management of DM is...
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To maintain sugar levels in the 70 -125 mg/dL range
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Prediabetes
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Diagnosed when fasting glucose levels are higher than normal (100 mg/dL) but lower than 126 mg/dL; Or when Glucose Tolerance Test is higher than normal (140 mg/dL) but lower than 199 mg/dL; Or when HbA1c levels are higher than normal (6.0%) but lower than 6.5% People with prediabetes usually develop type II diabetes within 10 years; Treat with weight loss and exercise to prevent onset of type II diabetes
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Tests for Diabetes are...
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Fasting Blood Glucose Glucose Tolerance Test HbA1c
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Diabetes can be diagnosed when...
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fasting glucose levels are 126 mg/dL or higher; Or when Glucose Tolerance Test is200 mg/dL or higher; Or when HbA1c levels are 6.5% or higher
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Type 1 Diabetes
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ONSET - Rapid AGE AT ONSET - Usually younger than 40 RISK FACTORS - Virus, autoimmune response, heredity USUAL BODY TYPE - Lean HIGH BLOOD GLUCOSE COMPLICATION - Ketoacidosis TREATMENT - Diet, exercise; Must have insulin to survive
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Type 2 Diabetes
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ONSET - Slow AGE AT ONSET - Usually older than 40 RISK FACTORS - heredity, obesity USUAL BODY TYPE - Obese HIGH BLOOD GLUCOSE COMPLICATION - Hyperosmolar hyperglycemia; may develop ketoacidosis TREATMENT - Diet, exercise; May need oral hypoglycemics or insulin to control blood glucose level
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Diabetes Goals and recommendations:
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-Capillary plasma glucose should be measured at least three times a day for patients using multiple insulin injections -BP measured every office visit -Serum creatnine and Urine microalbumin should be assessed yearly Target levels are: -HbA1c s/b <7% -preprandial capillary glucose s/b 70-130 mg/dL -Peak postprandial capillary glucose s/b < 180 mg/dL **(Blood glucose can be different in hospitalized patients) -BP s/b <130/80 mm Hg -LDLs s/b <100 mg/dL or < 70 mg/dL inpatients with cardiovascular disease -Triglycerides s/b 40 mg/dL in men >50 mg/dL in women
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More Diabetes Goals and recommendations:
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*Yearly flu vaccine for all patients 6mos and older *1 lifetime pneumococcal vaccine for patients older than 2, re-vaccination for patients older than 64 if first vaccine was more than 5 years earlier *Aspirin therapy 75-162 mg/day if older than 30 years *Statin therapy if history of CVD or if older than 40 with CVD risk factors *Smoking cessation counseling *Yearly comprehensive foot exam *Dilated comprehensive eye exam within onset of Type 1 diabetes, or at diagnosis of Type 2 diabetes, and annually thereafter
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Onset, Peak and Duration of VERY SHORT ACTING Insulins
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EXAMPLE- Insulin lispro BRAND NAME- Humalog ONSET- 5-15 min PEAK- 30-90 min DURATION- 5 hrs or less EXAMPLE- Insulin aspart BRAND NAME- Novolog ONSET- 10-20 min PEAK- 1-3 hrs DURATION- 3-5 hrs EXAMPLE- Insulin glulisine BRAND NAME- Apidra ONSET- 15-20 min PEAK- 30-90 min DURATION- 6 hrs
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Onset, Peak and Duration of SHORT ACTING Insulins
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EXAMPLE- Regular BRAND NAME- Humulin R, Novolin R ONSET- 30 min PEAK- 2-5 hrs DURATION- 5-8 hrs **Remember Rule of Odds 1-3-5
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INTERMEDIATE ACTING Insulins
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EXAMPLE- NPH BRAND NAME- Humulin N, Novolin N ONSET- 1-2 hrs PEAK- 6-12 hrs DURATION- 18-26 hrs **Remember Rule of evens 2-12-24 hrs
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Onset, Peak and Duration of BASAL Insulins
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EXAMPLE- Insulin glargine BRAND NAME- Lantus AE ONSET- 1-2 hrs PEAK- No Peak DURATION- Up to 24 hrs
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Onset, Peak and Duration of BASAL Insulins
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EXAMPLE- Insulin detemir BRAND NAME- Levemir ONSET- 1hr PEAK- No Peak DURATION- Up to 24 hrs
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What insulins can not be mixed with other insulins?
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glargine (Lantus) detemir (Levemir)
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Oral hypoglycemic agents ABSORPTION DELAYERS
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ALPHA-GLUCOSIDASE INHIBITORS (AGIs)-Lower postprandial glucose by reducing rate of carb digestion and absorption EXAMPLES- acarbose (Precose) miglitol (Glyset) S/E- Flatulance, Bloating NURSING IMPLICATIONS: -Give at start of each meal -No weight gain or hypoglycemia risk -Multiple dosing less convenient -If used in combination with another drug and hypoglycemia occurs, treat with milk or glucose tablets, not table sugar
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Oral hypoglycemic agents ABSORPTION DELAYERS
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DPP-4 INHIBITOR - Inhibits DPP-4, an enzyme that breaks incretins (hormones secreted by GI in response to food), they reduce glucogon secretion and increase insulin synthesis and release EXAMPLES- sitagliptin (Januvia) S/E- Upper respiratory infection, headache; hypoglycemia when administered in combination with a sulfonylurea NURSING IMPLICATIONS: -Administer one a day -Only works when blood glucose is high, so does not cause hypoglycemia when used alone -Watch for allergic reactions
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Oral hypoglycemic agents INSULIN SENSITIZERS
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BIGUANIDE- Decreases glucose production by liver; Increases glucose uptake by muscle EXAMPLES- metformin (Glocophage, Fortamet, Riomet, Glumetza) S/E- Nausea, diarrhea, decreased appetite, less likely to cause hypoglycemia than other agents NURSING IMPLICATIONS: -Give with meals -May enhance weight loss -Withhold if patient is having test with contrast dye -Contraindicated in renal and hepatic disease and heart failure -Monitor serum creatnine level -Notify physician of early symptoms of lactic acidosis; hyperventilation, myalgia, malaise
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Oral hypoglycemic agents INSULIN SENSITIZERS
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THIAZOLIDINEDIONES (glitazones)- reduce insulin resistancein muscles, Improve blood lipids, may lower blood pressure and improve cardiovascular risk EXAMPLES- pioglitazone (Actos) rosiglitizone (Avandia) S/E- Nausea, weight gain, fluid retention NURSING IMPLICATIONS: -Give with meals -Work well with obese patients -Avoid with liver disease; monitor liver enzymes -Monitor for heart failure -May alter effectiveness of some birth control pills.
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Oral hypoglycemic agents INSULIN STIMULATORS
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SULFONYUREAS- Stimulate insulin secretion by pancreas, increase insulin receptor sensitivity EXAMPLES- glipizide (Glucotrol) glimepride (Amaryl) glyburide (Micronase, Diabeta) S/E- Hypoglycemia, weight gain, possible increased risk of cardiovascular disease NURSING IMPLICATIONS: -Monitor patient for hypoglycemia -Teach patient to avoid alcohol
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Subjective data collection for patient with DM
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-Age and symptoms at onset -Understanding of Diabetes (1 & 2) and self care -Current treatment plan (medication, nutrition therapy, exercise) and adherence to plan -Frequency of blood glucose monitoring and pattern of BG levels (check diary) -History of diabetes related complications -Involvement of family or other support systems
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Objective data collection for patient with DM
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-Vital signs -Height, Weight, Body Mass Index -Skin, Integrity Turgor, condition of injection sites -Feet; pulses, color, temp, skin integrity, pressure points, sensation -Lab results: blood glucose, HbA1c, creatnine, lipid profile, albuminuria, urine and serum ketones
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One of the risk factors for type 2 diabetes is...
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Obesity
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Which symptom is commonly associated with hyperglycemia?
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Polyuria
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Protein in the urine is a sign of which long-term complication of diabetes?
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Nephropathy
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What is the best way for patients to avoid long-term complications of diabetes?
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Maintain pre-meal blood glucose levels under 1.30 mg/dL
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What is a breakfast menu must appropriate for a patient with diabetes?
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One slice whole grain toast with peanut butter, skim milk, orange juice
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Correct sequential order for mixing insulin
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1. Roll cloudy vial 2. Clean vial tops with alcohol 3. Inject air into cloudy insulin 4. Inject air into clear insulin 5. Draw up clear insulin 6. Draw up cloudy insulin
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A patient who is preparing for surgery asks the nurse why his physician took him off his oral hypoglycemic and placed him on sliding-scale insulin. Which response by the nurse is best?
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"It helps us to maintain better control of your blood glucose during surgery. you will most likely be back on pills before you go home."
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Which meal plan is best for the patient with reactive hypoglycemia?
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Small, frequent meals
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Glucose in urine is called
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Glycosuria
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Too much sugar in the blood is called...
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Hyperglycemia
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Too little sugar in the blood is called...
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Hypoglycemia
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Deep, sighing respiration's from diabetic acidosis are called...
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Kussmaul's respirations
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Excessive hunger is called...
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Polyphagia
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Excessive thirst is called...
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Polydipsia
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The patient who gets up to urinate at night has...
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Nocturia
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The time when insulin is working its hardest after injection is called...
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Peak Action Time
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The length of time insulin works is called its...
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Duration
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The Diabetes Control and Complications Trial (DCCT) found that individuals who maintain _______ control of their diabetes will have fewer long-term complications.
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Tight
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Hypoglycemia symptoms
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Tremor Irritability Sweating
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Hyperglycemia symptoms
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Polydipsia Polyuria Lethargy Fruity Breath Abdominal Pain
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Retinopathy
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SYMPTOM- Impaired vision
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Neuropathy
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SYMPTOM- Burning pain in legs and feet
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Hyperosmolar hyperglycemia
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SYMPTOM- Profound hyperglycemia without ketonemia
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Diabetic Ketoacidosis
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SYMPTOM- Ketones in the blood and urine
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Nephropathy
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SYMPTOM- Microalbuminuria
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Gastroparesis
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SYMPTOM- Food intolerance
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Infection
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SYMPTOM- Fever
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What is an acceptable pre-meal blood sugar range for a patient with diabetes?
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70-130 mg/dL
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Before giving insulin, the nurse always checks which result?
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Blood sugar level
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At what point after injection does the peak action of regular insulin occur?
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2-5 hours
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What is a symptom of hypoglycemia?
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Cold sweats and Tremors
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In addition to stimulating insulin production, glyburide (Micronase) has what effects?
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Increases tissue sensitivity to insulin
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A 26 yr old patient is admitted to the hospital with a new diagnosis of diabetes, a blood glucose of 690 mg/dL, and ketones in the blood and urine. Which type of diabetes should the nurse expect?
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Type 1
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A 45 yr old with diabetes forgot to take a daily dose of glyburide (Micronase). What symptom should the nurse be vigilant about ?
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Fatigue, thirst, blurred vision
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Which routes can Insulin be administered?
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Intravenous (IV) Sub Q Intramuscular
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While providing discharge instructions to a patient newly taking NPH insulin every morning, the nurse recognizes that teaching has been effective if the patient knows to observe for signs and symptoms of low blood sugar level at which of the following times?
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6-12 hours after administration of insulin
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A patient with newly diagnosed diabetes asks the nurse what to take for low blood sugar. What would be appropriate for the nurse to suggest?
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Raisins
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The nurse recognizes that teaching is effective if a patient with diabetes knows to use sub Q glucagon for an emergency episode of which of the following conditions?
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Hypoglycemia
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A patient on an American Diabetes Association diet receives a breakfast tray and does not care for the oatmeal. What is a food can the nurse substitute for a 1/2 cup of oatmeal?
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A slice of wheat toast
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Oral hypoglycemic agents COMBINATION AGENTS
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EXAMPLES- metformin and glyburide (Glucovance) metformin and rosiglitazone (Advandamet) glipizide and metformin (Metaglip) S/E- See individual agents NURSING IMPLICATIONS: -See individual agents
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Diabetes Summary
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SIGNS AND SYMPTOMS: Polyuria Polydipsia Polyphagia Fatigue Blurred Vision Headache Abdominal pain DIAGNOSTIC TESTS: Fasting Plasma Glucose HbA1c (glycosylated hemoglobin) Oral glucose tolerance test Additional testing for complications THERAPUTIC MEASURES: Nutrition Therapy Exercise Insulin Oral hypoglycemic medication Self monitoring of blood glucose levels Education COMPLICATIONS: Hypoglycemia Hyperglycemia Diabetic ketoacidosis Hyperosmolar hyperglycemia Long-term complications PRIORITY NURSING DIAGNOSIS: Risk for Unstable Blood Glucose Level
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