CH 17 blood – Flashcards
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In a centrifuged sample of blood, what should NOT be in the plasma portion of the sample?
albumin
platelets
electrolytes
fibrinogen
answer
platelets
Platelets are dense enough that they should be in the buffy coat layer.
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Which of these represents the majority of whole blood by volume?
leukocytes
platelets
plasma
erythrocytes
answer
plasma
Plasma typically constitutes 55% of whole blood, although this value can vary somewhat.
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What is the name of the protein found in erythrocytes that transports respiratory gases?
antibodies
fibrinogen
albumin
hemoglobin
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hemoglobin
Other than water, hemoglobin makes up almost the entire contents of an erythrocyte. It can bind both oxygen and carbon dioxide.
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What triggers erythropoietin (EPO) production to make new red blood cells?
too many platelets
reduced availability of oxygen
excess oxygen in the bloodstream
a high hematocrit
answer
reduced availability of oxygen
Reduced oxygen delivery to the kidneys will result in the release of erythropoietin (EPO), which in turn promotes the release of more erythrocytes from the bone marrow.
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How many oxygen molecules can be transported by one hemoglobin molecule?
two
four
eight
answer
four
Each Fe2+ ion can bind to a single oxygen molecule.
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Which of the formed elements is present in the greatest concentration?
agranular leukocytes
platelets
granular leukocytes
erythrocytes
answer
erythrocytes
The erythrocytes (red blood cells) make up about 45% of whole blood.
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All lymphocytes are also leukocytes.
True
False
answer
True
Lymphocytes are specialized leukocytes. Lymphocytes include T cells, B cells, and natural killer cells.
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Which of the following is NOT a function of blood?
distribution
regulation
hormone production
protection
answer
hormone production
The blood does not produce hormones.
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Which formed element can be described as membrane-enclosed cytoplasmic fragments?
lymphocytes
platelets
erythrocytes
monocytes
answer
platelets
Platelets can be referred to as cytoplasmic fragments because they form as packets of cytoplasm are pinched off the megakaryocyte.
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Choose the incompatible transfusion.
Donate type O blood to a recipient with type AB blood.
Donate type A blood to a recipient with type AB blood.
Donate type B blood to a recipient with type AB blood.
Donate type B blood to a recipient with type O blood.
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Donate type B blood to a recipient with type O blood.
A person with type B blood can only give blood to people of type AB and B blood.
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Granulocytes called neutrophils are phagocytic and are the most numerous of all white blood cell types.
True
False
answer
true
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What part of the body does erythropoietin (EPO) target to increase erythropoiesis?
kidneys
bone marrow
liver
lungs
answer
bone marrow
The bone marrow, specifically red marrow, is the site of blood cell production and is stimulated by erythropoietin.
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Which ABO blood type is considered to be the universal recipient?
B
O
A
AB
answer
AB
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A person who lacks agglutinogen A but has agglutinogen B would have blood type __________.
A
AB
O
B
answer
B
Someone with type B blood only has agglutinogen B on their erythrocytes.
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What is a hematocrit?
Hematocrit is the percentage of erythrocytes in a whole blood sample.
Hematocrit is the percentage of all formed elements in a whole blood sample.
Hematocrit is the percentage of leukocytes and platelets in a whole blood sample.
Hematocrit is the percentage of plasma in a whole blood sample.
answer
Hematocrit is the percentage of erythrocytes in a whole blood sample.
Although the percent sign is usually omitted, the hematocrit, which in this figure is 45, is the percentage of erythrocytes in whole blood. The height of the erythrocyte layer is divided by the total height of the material.
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Which of these is true of the materials making up the buffy coat in centrifuged blood?
They are intermediate in density between erythrocytes and plasma.
They are denser than erythrocytes but less dense than plasma.
They are less dense than both erythrocytes and plasma.
They are denser then plasma and erythrocytes.
answer
They are intermediate in density between erythrocytes and plasma.
Centrifugation separates materials by density. Materials in the buffy coat are intermediate in density between erythrocytes and plasma.
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Which of the following is NOT a formed element in whole blood?
erythrocytes
platelets
leukocytes
albumin
answer
albumin
Albumin is a protein that would be found in the plasma.
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Mature erythrocytes lack a nucleus.
True
False
answer
true
One of the structural characteristics of erythrocytes is the lack of a nucleus. This leads to a biconcave disk shape in the cell that increases the surface area to volume ratio. Additionally, RBCs lack mitochondria.
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Which of the following does NOT stimulate erythrocyte production?
a drop in normal blood oxygen levels
testosterone
erythropoietin
hyperventilating
answer
hyperventilating
Hyperventilating leads to an above-normal level of oxygen in the blood, which would not stimulate RBC production.
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What organ in the body regulates erythrocyte production?
pancreas
liver
brain
kidney
answer
kidney
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Each hemoglobin molecule can transport two molecules of oxygen.
True
False
answer
false
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Which granulated leukocyte is most likely to be active during a bacterial infection?
lymphocytes
basophils
monocytes
neutrophils
answer
neutrophils
Neutrophils are active in phagocytizing bacteria.
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Which of the choices below is the parent cell for all formed elements of blood?
polymorphonuclear cell
hemocytoblast
normoblast
megakaryocyte
answer
hemocytoblast
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All lymphocytes are leukocytes, but not all leukocytes are lymphocytes.
True
False
answer
true
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Hemostasis is important for __________.
red blood cell recycling
red blood cell production
stoppage of bleeding
white blood cell production
answer
stoppage of bleeding
Hemostasis leads to stoppage of bleeding. The hemostasis response is fast, localized, and controlled. It involves clotting factors and substances released by damaged tissue and platelets.
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Which step in hemostasis involves activation of formed elements in the blood?
platelet plug formation
coagulation
fibrin production
vascular spasm
answer
platelet plug formation
Platelets are formed elements that are activated by damaged tissue. Platelets for a temporary plug preventing blood loss.
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The immediate response to blood vessel injury is clotting.
True
False
answer
false
the immediate response is vascular spasm
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AB blood type is the universal blood recipient because of that type's lack of agglutinogens.
True
False
answer
false
AB blood type is the universal blood recipient because of that type's lack of antibodies.
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A mismatch of blood types during a transfusion is dangerous because ________.
antibodies in the donor's plasma will attack and kill the recipient's healthy blood cells
white blood cells from the donor's blood cause inflammation
clotting factors in the donor's blood will cause unwanted clots known as thrombus
preformed antibodies in the recipient's blood will bind and clump (agglutinate) the donated cells
answer
preformed antibodies in the recipient's blood will bind and clump (agglutinate) the donated cells
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Which blood type is generally called the universal donor?
O
AB
A
B
answer
O
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An individual who is blood type AB negative can ________.
receive any blood type in moderate amounts except that with the Rh antigen
donate to types A, B, and AB, but not to type O
receive types A, B, and AB, but not type O
donate to all blood types in moderate amounts
answer
receive any blood type in moderate amounts except that with the Rh antigen
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Which statement is true?
A person with type AB blood does produce agglutinins.
Type O is the universal recipient.
Type A blood cannot be given to people with type B blood.
Type AB is the universal donor.
answer
Type A blood cannot be given to people with type B blood.
People with type B blood produce antibodies against A type blood, this transfusion would cause a cross reaction.
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A person with type B blood could receive blood from a person with either type B or type O blood.
True
False
answer
true
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What percentage of our blood is plasma?
A. 90%
B. 55%
C. 45%
D. 65%
answer
B. 55%
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After centrifuging, of the listed blood components, which contains the components of immune function?
A. Plasma
B. Buffy coat
C. Erythrocytes
D. Hematocrit
answer
B. Buffy coat
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Which of the following is present in a red blood cell?
a. Nucleus
b. Plasma membrane
c. Ribosome
d. Mitochondrion
answer
b. Plasma membrane
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Each hemoglobin can transport ________ oxygen atoms.
A. 4
B. 40
C. 400
D. 4000
answer
A. 4
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Oxygen binds to the _______ portion of hemoglobin.
A. globin
B. oxyhemoglobin
C. iron atom
D. amino acid
answer
C. iron atom
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A hematopoietic stem cell will give rise to __________.
A. erythrocytes
B. leukocytes
C. platelets
D. all of the above
answer
D. all of the above
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What response would you expect after traveling to high altitude for two weeks?
A. Blood levels of oxygen would remain depressed for the duration.
B. A surge in iron release from the liver would occur.
C. The kidneys would secrete elevated amounts of
erythropoietin.
D. There would be no change in blood composition.
answer
C. The kidneys would secrete elevated amounts of
erythropoietin.
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The target organ of erythropoietin is the ______.
A. kidney
B. liver
C. thymus
D. red bone marrow
answer
A. kidney
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An elevated neutrophil count would be indicative of ________.
A. an allergic reaction
B. a cancer
C. an acute bacterial infection
D. a parasidic infection
answer
C. an acute bacterial infection
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Why don't platelets form plugs in undamaged vessels?
A. Platelets aren't formed until vessel damage occurs.
B. Only contact of platelets with exposed collagen fibers causes them to be sticky and form plugs.
C. Plugs do form, but are removed by macrophages.
D. Platelets don't form plugs, it is the megakaryocytes that form the plugs.
answer
B. Only contact of platelets with exposed collagen fibers causes them to be sticky and form plugs.