CH. 14 (cell/mol) – Flashcards
Unlock all answers in this set
Unlock answersquestion
Receptor-ligand binding, signal transduction, cellular response, change in gene expression
answer
Which answer shows the correct order of the flow of information during cell signaling?
question
exchange of GDP for GTP on Gα
answer
Which of the following represents a "molecular switch" that activates Gα proteins?
question
D
answer
Which of these acts as a second messenger?
question
A
(This is a signal molecule. The attachment of a signal molecule to a plasma membrane receptor initiates a signal transduction pathway.)
answer
Which of these is responsible for initiating a signal transduction pathway?
question
By binding to DNA it triggers the transcription of a specific gene.
answer
What role does a transcription factor play in a signal transduction pathway?
question
Activated transcription factors trigger transcription.
answer
In this animation, which of the following, when activated by a signal transduction pathway, moved from the cytoplasm to the nucleus of a cell?
question
A
answer
Which of these is a membrane receptor?
question
Signal molecule
answer
A signal transduction pathway is initiated when a ____________ binds to a receptor.
question
Cyclic AMP
answer
What can act as a second messenger?
question
Endoplasmic reticula (stores calcium ions)
answer
Calcium ions that act as second messengers are stored in ____________.
question
Phospholipase C, IP3, Ca2+
Phospholipase C (Cleaves IP3 from a membrane protein, and IP3 then binds to a calcium channel on the ER.)
answer
__________ catalyzes the production of __________, which then opens an ion channel that releases _________ into the cell's cytoplasm.
question
Amplification
(By activating many other molecules the initial signal is amplified.)
answer
A protein kinase activating many other protein kinases is an example of __________.
question
B
answer
Which of these is a receptor molecule?
question
Signal molecule
(The binding of a signal molecule to a receptor initiates a signal transduction pathway.)
answer
A signal transduction pathway is initiated when a __________ binds to a receptor.
question
A
answer
Which of these is a signal molecule?
question
Ligand
answer
A signal molecule is also known as a(n) ___________.
question
Transduction
answer
Which of these is the second of the three stages of cell signaling?
