Carboplatin C6H12N2O4Pt structure – Flashcards

Flashcard maker : Roy Johnson

Molecular Formula C6H12N2O4Pt
Average mass 371.254 Da
Density
Boiling Point
Flash Point
Molar Refractivity
Polarizability
Surface Tension
Molar Volume
  • Experimental data
  • Predicted – ACD/Labs
  • Predicted – ChemAxon
  • Experimental Physico-chemical Properties
    • Experimental Melting Point:

      228-230 °C LKT Labs
      [C0171]
    • Experimental Solubility:

      10 mM in DMSO MedChem Express HY-17393
      DMSO < 1mg/ml; Water <1 mg/ml MedChem Express http://www.medchemexpress.com/levomefolate-calcium.html
      Soluble in water. LKT Labs
      [C0171]
  • Miscellaneous
    • Safety:

      Danger Biosynth W-106301
      GHS07; GHS08 Biosynth W-106301
      H302; H312; H332; H317; H334; H360 Biosynth W-106301
      H340 H360D H302 H332 H334 H317 LKT Labs
      [C0171]
      Not dangerous goods. LKT Labs
      [C0171]
      P201; P261; P280; P308+P313 Biosynth W-106301
      R46;R61;R20/21;R42/43 LKT Labs
      [C0171]
      Xn, Carc., Repr. LKT Labs
      [C0171]
    • Compound Source:

      synthetic Microsource
      [01502106]
    • Bio Activity:

      Carboplatin is a chemotherapy drug by binding to DNA and interfering with the cell’s repair mechanism.; IC50 Value: ; Target: DNA crosslinker; in vitro: Carboplatin exhibits an inhibitory effect on cell proliferation in a human ovarian cancer cell line panel, including A2780, SKOV3, and IGROV-1 cells with IC50 of 6.1 ?M, 12.4 ?M and 2.2 ?M, respectively [1]. MedChem Express HY-17393
      Cell Cycle/DNA Damage MedChem Express HY-17393
      Cell Cycle/DNA Damage; MedChem Express HY-17393
      DNA alkylator/crosslinker MedChem Express HY-17393

Predicted data is generated using the ACD/Labs Percepta Platform – PhysChem Module

No predicted properties have been calculated for this compound.

Density:
Boiling Point:
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Index of Refraction:
Molar Refractivity:
#H bond acceptors:
#H bond donors:
#Freely Rotating Bonds:
#Rule of 5 Violations:
ACD/LogP:
ACD/LogD (pH 5.5):
ACD/BCF (pH 5.5):
ACD/KOC (pH 5.5):
ACD/LogD (pH 7.4):
ACD/BCF (pH 7.4):
ACD/KOC (pH 7.4):
Polar Surface Area:
Polarizability:
Surface Tension:
Molar Volume:

Click to predict properties on the Chemicalize site

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