Biology Meiosis – Flashcards

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question
What is the difference between diploid and haploid cells? If haploid cells have "N" number of chromosomes, how many do diploid cells have?
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Diploid cells have a full set of chromosomes - 23 pairs of two chromosomes. (46) Haploid cells have only 23 chromosomes - half of a set. If haploid cells have N chromosomes, then diploid cells have 2N.
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For what reason must human gametes be haploid cells, not diploid cells?
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Gametes must be haploid because two gametes fuse together to make a diploid cell, a zygote. Since we are fusing two cells together, they must each have half as many chromosomes as the final cell must have.
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Prophase I
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-*Chromatin condenses into chromosomes* and the nuclear membrane dissolves. -*Homologous chromosomes pair up*; these pairs are referred to as tetrads. -*Crossing-over* occurs between the homologous chromosomes, causing them to swap parts of their DNA. -*Spindle fibers* attach to the tetrads.
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Metaphase I
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*The tetrads line up along the center of the cell* . Each tetrad is *randomly oriented*, so which chromosomes end up in which daughter cells is random.
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Anaphase I
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*The tetrads are pulled apart,* with each chromosome in the tetrad being pulled by the spindle fibers to one or the other end of the cell.
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Telophase I
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Cytokinesis is occurring, leading to cell division. The nuclear membrane does not reform.
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Prophase II
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In each daughter cell, the chromosomes - now unpaired - are attached to by the spindle fibers again.
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Metaphase II
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The chromosomes line up in the middle of the cell.
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Anaphase II
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Each of the two chromatids which make up the chromosomes are pulled to one or the other end of the cell, causing the separation of the chromatids.
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Telophase II
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The nuclear membrane reforms. Cytokinesis is occurring, leading to another cell division.
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What makes two chromosomes homologous, and why is this important?
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Two chromosomes are homologous if they have the exact same genes on them. They may have different alleles of those genes, but not different genes. This is important because only homologous chromosomes (or the X and Y chromosomes, with each other) can pair up during prophase I.
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What is a tetrad? When does it form?
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A tetrad is a pair of homologous chromosomes. It forms during prophase I.
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What is crossing over and when does it occur? Why is it important?
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Crossing over is when two chromosomes "overlap", resulting in the two chromosomes swapping two sections of DNA with each other. These sections always contain the same genes as each other.
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Can chromosomes that are not homologous cross over with each other? What effect might this have on how the sex chromosomes behave during meiosis?
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Only homologous chromosomes can cross over with each other; thus, in males, the X and Y chromosomes do not cross over as they are not homologous, even though they will pair for the purpose of being split apart evenly.
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How is meiosis similar to mitosis? How is it different?
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They are both processes of cell division in which genetic material is split between the two cells being produced. In both, the centrioles extend spindle fibers which attach to the centromeres of the chromosomes, line them up in the middle of the cell, and then split them apart; after this, cytokinesis occurs and the cell divides. However, meiosis is a more complicated process; it has two stages, meiosis I and meiosis II, each of which is a cell division. While meiosis II is the same as mitosis, meiosis I is significantly different. It involves the splitting of homologous pairs of chromosomes, not just sister chromatids, as well as crossing over between the homologous pairs. Finally, the end goal of the two processes are very different: mitosis produces two genetically identical cells, while meiosis produces four genetically different cells.
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Where in the body does meiosis (that is, spermatogenesis and oogenesis) occur?
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In the testes for males and the ovaries for females.
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What are the three major differences between spermatogenesis and oogenesis, other than that one takes place in males and the other in females?
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a. Spermatogenesis occurs constantly throughout a mature male's lifespan, while oogenesis begins with a set number of eggs at birth, though it is not completed until after the onset of puberty. b. Oogenesis only results in one ovum (egg) and three mostly-useless polar bodies that cannot be fertilized, while spermatogenesis forms four fully functional spermatozoa. c. Spermatogenesis takes only a few hours. Oogenesis is completed once every 28 days.
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What is a karyotype and how do we use it to identify genetic disorders?
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A karyotype is an organized image of an organism's chromosomes, arranged with the homologous chromosomes in pairs and from the largest to the smallest chromosomes. We can identify some genetic disorders that are caused by an individual having more or fewer chromosomes than normal by producing a karyotype from one of their cells.
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What is an autosome?
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An autosome is a chromosome that is not a sex chromosome. In humans, pairs 1-22 are autosomes.
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What is nondisjunction? How can this affect gametes and offspring?
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Nondisjunction is when chromosomes or chromatids do not separate properly in anaphase I or II. This can result in gametes containing more or fewer chromosomes than they should, and if those gametes participate in fertilization, the result will be a zygote with more or fewer chromosomes than normal.
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Turner Syndrome
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An individual with Turner Syndrome has only one X and no Y chromosomes.
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Down Syndrome
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An individual with Down Syndrome has three copies of chromosome 21, rather than just two.
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Klinefelter Syndrome
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An individual with Klinefelter Syndrome is a male with more than one X chromosome - usually just one extra, but rarely, more.
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XYY Syndrome
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As the name implies, an individual with XYY Syndrome has two Y chromosomes rather than just one.
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