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ATI The Immune System

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A health care professional should understand that raltegravir (Isentress) treats patients who have which of the following?
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Resistant HIV disease This drug should be given along with other antiretroviral drugs.
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When considering drug therapy options for a patient who has metastatic breast cancer that is positive for human epidermal growth factor receptor 2 (HER2), the health care professional should choose which of the following drugs?
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Trastuzumad (Herceptin) A monoclonal antibody treats metastatic breast cancer with tumors that over express.
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A health care professional is caring for a patient who is about to begin receiving cisplatin to treat testicular cancer. The health care professional should tell the patient to report which of the following adverse effects? (Select all that apply.)
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Paresthesias Sore Throat Flank Pain Tinnitus
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A health care professional is assessing a patient following a trastuzumab (Herceptin) infusion to treat metastatic breast cancer. Which of the following findings indicates an adverse reaction to the drug? (Select all that apply.)
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Wheezing Dysrhythmias Hypotension Dever
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When caring for a patient who is receiving vincristine to treat lung cancer, the health care professional should monitor for which of the following findings that indicates an adverse effect?
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Weak Hand Grasps Can cause peripheral neuropathy.
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A health care professional is caring for a patient who is about to begin taking imatinib (Gleevec) to treat chronic myeloid leukemia. Which of the following instructions should the health care professional include when talking to the patient about taking the drug? (Select all that apply.)
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Clean fruits and vegetables thoroughly. Weigh yourself daily. Perform hand hygiene frequently. Avoid herbal supplements.
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A health care professional is about to administer enfuvirtide (Fuzeon) to a patient. The health care professional should perform which of the following actions? (Select all that apply.)
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Administer the drug subcutaneously. Roll the vial gently to reconstitute the solution. Inject the solution at room temperature.
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A health care professional should understand that enfuvirtide (Fuzeon) is an appropriate choice for patients who have which of the following?
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Advanced HIV disease
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A health care professional is caring for a patient who is about to begin maraviroc (Selzentry) therapy. The health care professional should tell the patient to reprot which of the following adverse effects of the drug? (Select all that apply.)
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Paresthesias Cough Jaundice Fever
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A health care professional should question the use of maraviroc (selzentry) for a patient who has which of the following?
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Non-chemokine receptor 5 (CCR5)-tropic HIV-1
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When talking to a patient who is about to begin vincristine therapy to treat lymphoma, the health care professional should include which of the following instructions?
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Increase fiber intake. Vincristine can cause severe constipation and upper colon fecal impaction.
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A health care professional is caring for a patient who is about to begin delavirdine (Rescripto) therapy to treat HIV-1. The health care professional should tell the patient to report which of t he following adverse reactions to the drug?
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Rash Rash can develop into Stevens-Johnson syndrome.
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A health care professional is caring for a patient who is reciving IV carmustine (BiCNU) to treat multiple myeloma. The health care professional should recognize that the patient is at the greatest risk for infection for which of the following lengths of time after the infusion.
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4 to 6 weeks
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When talking with a patient who is about to begin methotrexate (Trexall) therapy to treat non-Hodgkin lymphoma, the health care professional should include which of the following instructions.
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Use a soft-bristled toothbrush. To prevent gum bleeding and mouth trauma.
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A health care professional is about to administer IV paclitaxel (Taxol) to a patient who has ovarian cancer. Which of the follwoing actions should the health care professional take? (Select all that apply.)
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Give the patient an antihistamine. (prevent hypersensitivity reaction) Administer the drug through non-PVC tubing. Use an in-line filter.
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A health care professional is caring for a patient who is about to start ritonavir (Norvir) and zidovudine (Retrovir) therapy to treat HIV-1. The health care professional should explain that the patient will recieve ritonavir along with at least one reverse transcriptase inhibitor to
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prevent drug resistance.
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A health care professional is caring for a patient who is about to begin taking mercaptopurine (Purinethol) to treat leukemia. Which of the following instructions should the health care professional include when talking with the patient about the drug? (Select all that apply.)
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Use contraception if pregnancy is a risk. (Pregnancy Category D) Perform oral hygiene frequently. (can cause stomatitis) Perform hand hygiene frequently. (can cause neutropenia.) Avoid activities that can cause injury. (can cause thrombocytopenia.)
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A health care professional should question the use of cyclophosphamide for a patient who has which of the following?
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Dehydration Patients who have a fluid-volume deficit because dehydration increases the risk for renal toxicity.
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Unless there are any specific contraindications, which of the following immunizations should adults receive once each year.
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Influenza
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A health care professional should question the use of anastrozole (Arimidex) for a patient who is
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premenopausal. It is only used in women who are postmenopausal women.
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When caring for a patient who is taking flutamide to treat prostate cancer, the health care professional should monitor the patient for which of the following adverse effects of the drug?
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Gynecomastia (growth of breast tissue, decreased libido, and impotence).
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While assessing a patient who is receiving interfreon alfa-2a (Roferon-A) to treat Kaposi’s sarcoma, the health care professional should check for which of the following possible indications of an adverse reaction?
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Fever Can cause a flu-like reaction, manifesting as fever, myalgia, and fatigue.
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A health care professional is caring for a patient who is about to begin topotecan (Hycamtin) therapy to treat resistant, small-cell lung cancer. The health care professional should caution the patient about taking which of the following types of over-the-counter drugs while receiving the therapy?
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Ibuprofen (Advil) NSAIDs, anticoagulants, and antiplatelet drugs increase the patient’s risk for bleeding.
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A health care professional is caring for a patient who is about to begin taking tamoxifen (Soltamox) to treat breast cancer. The health care professional should recognize the need for cautious use of the drug if the patient also has which of the following?
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Cataracts Can cause retinopathy, cataracts, and decreased visual acuity.
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A health care professional is caring for a patient who is about to begin intrathecal cytrabine (DepoCyt) therapy to treat meningeal leukemia. The health care professional should explain that the patient should also receive which of the following drugs to reduce the risk of neurotoxicity?
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Dexamethasone To help reduce the inflammation of the arachnid that the drug can cause.