Anatomy and Physiology #2 Endocrine system – Flashcards
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Which of the following hormones is a part of the rapid response (rather than the prolonged response) to stress?
cortisol
epinephrine
aldosterone
ADH (vasopressin)
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Epinephrine
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In response to stress, which of the following changes would happen?
decreased sweating
decreased cardiac output
decreased or difficulty breathing
decreased insulin secretion
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decreased insulin secretion
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Which of the following are symptom(s) of pheochromocytoma?
cool, dry skin
heart palpitations
slow heart rate
low blood glucose
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heart palpitations
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Choose which condition has all of the following symptoms: hypertension, hyperglycemia, and a "moon face."
Addison's disease
pheochromocytoma
Cushing's disease
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Cushing's disease
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What hormone also aids the stress response by promoting water retention and acting as a vasoconstrictor?
ADH (vasopressin)
cortisol
angiotensin II
aldosterone
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ADH (Vasopressin)
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Compared to the endocrine system, the nervous system is __________.
more localized in action
briefer in action
more rapidly acting
Compared to the endocrine system, the nervous system has all of these characteristics.
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All of these
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In paracrine communication a chemical signal acts within the tissue that produced it; in endocrine communication the signal reaches the target cells by way of the circulation. Are these two statements true or false?
The first is false; the second is true.
The first is true; the second is false.
Both statements are false.
Both statements are true.
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Both statements are true
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Endocrine cells __________.
contain secretory vesicles
perform intercellular communication
secrete into extracellular fluid
Endocrine cells have all of these characteristics.
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Endocrine cells have all of these characteristics
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What is the order of the effects on intracellular hormone binding
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-Diffusion through membrane lipids
-Binding of hormone to cytoplasmic or nuclear receptors
-Binding of hormone receptor complex to DNA
-Gene activation
-Transcription and mRNA production
-Translation and protein synthesis
-Alteration of cellular structure of activity and subsequent target cell response
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Which of the following hormones has intracellular receptors?
cortisol
insulin
epinephrine
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Cortisol
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What is the mechanism of action of lipid-soluble hormones?
increasing protein kinases
phosphorylation of intracellular proteins
activation of genes, which increases protein synthesis in the cell
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activation of genes, which increases protein synthesis in the cell
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After a lipid-soluble hormone is bound to its intracellular receptor, what does the hormone complex do?
directly alters protein synthesis at the ribosome
acts as a transcription factor and binds to DNA, activating a gene
activates a protein kinase
phosphorylates a protein
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Acts as a transcription factor and binds to DNA, activating a gene.
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hat type of hormones bind to receptors located on the cell membrane?
lipid-soluble hormones, such as thyroid hormones and cortisol
water-soluble hormones, such as insulin and epinephrine
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water soluble hormones
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Which is the correct order of events for hormones activating Gs proteins?
A. activation of G protein, binding of GTP, activation of adenylate cyclase, conversion of ATP to cAMP
B. activation of G protein, binding of GTP, activation of phospholipase C, activation of DAG and IP3
C. activation of a G protein, tyrosine kinase receptor, phosphorylation of intracellular proteins
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A
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Which of the following hormones does the gland indicated by the arrow secrete?
Epinephrine
Calcitonin
Oxytocin
Insulin
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The thyroid gland, in the neck, secretes calcitonin.
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What is the chemical classification of this hormone?
Catecholamine
Protein
Carbohydrate
Steroid
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Steroid hormones diffuse through the plasma membrane and bind to an intracellular receptor.
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Which of the labels in the figure indicate the source of antidiuretic hormone?
The cells in the pituitary labeled D
The hypothalamic nuclei labeled B
The hypothalamic nuclei labeled C
The hypothalamic nuclei labeled A
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These nuclei send impulses to the posterior pituitary, from which ADH is released.
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Lipid-soluble hormones usually bind to __________ receptors.
intranuclear
G-protein coupled
transmembrane
extracellular
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Intranuclear
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Which of these hormones is not derived from an amino acid?
epinephrine
thyroid hormone
parathyroid hormone
norepinephrine
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Parathyroid hormone
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Peptide hormones ___________.
always contain one sugar molecule
are composed of amino acids
usually bind to intranuclear receptors
are lipid soluble
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are composed of amino acids
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Which hormone secreted by the pituitary gland causes the thyroid gland to release thyroid hormones?
ACTH
TSH
MSH
GH
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TSH
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The release of ACTH from the anterior lobe of the pituitary gland causes the _______.
adrenal cortex to release glucocorticoids
mammary glands to secrete milk
gonads to release sex hormones
melanocytes to secrete melanin
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adrenal cortex to release glucocorticoids
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Which hormone affects the smooth muscle of the ductus deferens and uterus?
PRL
FSH
OXT
ADH
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OXT
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Which of the following hormones is regulated by a neuroendocrine ("letdown") reflex?
antidiuretic hormone (ADH)
oxytocin
cortisol
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Oxytocin
(Yes, suckling of the infant (or stretching of the uterus) increases release of oxytocin, which causes the milk let-down effect (or increased uterine contractions).)
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Where is antidiuretic hormone (ADH), also known as vasopressin, synthesized?
hypothalamus
anterior pituitary
posterior pituitary
kidney
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Hypothalamus
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What is the most important regulatory factor controlling the circulating levels of thyroid hormone?
thyroid-stimulating hormone (TSH)
a circadian rhythm of release
negative feedback
thyrotropin-releasing hormone (TRH)
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negative feedback
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The brain region that exerts the most direct effects on the endocrine system is the __________.
thalamus
mesencephalon
pons
hypothalamus
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Hypothalamus
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Which of these hormones exerts a strong effect on adrenal steroid production?
LH
ADH
ACTH
TSH
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ACTH
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Which of these is released by the neurohypophysis?
TSH
ADH
ACTH
FSH
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ADH
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Which of these signs is often seen in patients suffering from hyperthyroid disease?
elevated body temperature
elevated oxygen utilization
elevated heart rate
Patients with hyperthyroidism often exhibit all of these signs.
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All of these
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Which chemical element is necessary to make thyroid hormone?
iodine
thorium
calcium
iron
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Iodine
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Which gland is named for a nearby prominent cartilage?
thyroid
pituitary
adrenal
salivary
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Thyroid
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Which of the following is regulated by the gland indicated by the red arrow?
Blood calcium concentration
Body's reaction to stress
Blood pressure
Blood glucose concentration
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Blood calcium concentration
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What is the role of PTH?
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PTH, that elevates blood calcium concentration.
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Which of these statements about the parathyroid gland is false?
They secrete a peptide hormone.
There are usually four glands.
It is posterior to thyroid.
The hormone release is triggered by a rise in blood calcium.
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The hormone release id triggered by a rise in blood calcium
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Which of these might result from excessive parathyroid hormone release?
osteopenia
elevated blood calcium
increased loss of bone minerals
All of these might result from excessive parathyroid hormone release.
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All of these
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Which of the following could occur with a hypersecreting tumor of this gland?
Elevation of blood pressure and blood glucose concentration
Excess output of dilute urine
Enlargement of bones and cartilage
Appearance of a lump in the neck
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Elevation of blood pressure and blood glucose concentration
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Excessive secretion by the adrenal medulla can lead to all of these changes except __________.
elevated heart rate
elevated blood pressure
drowsiness
elevated blood glucose level
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Drowsiness
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Which of these statements about the pineal gland is false?
It produces melatonin.
It promotes sleep.
It is controlled by adenohypophysis.
It receives inputs from the retina.
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It is controlled by the adenohypophysis
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The __________ gland secretes melatonin.
pituitary
neurohypophysis
thymus
pineal
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Pineal
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When blood glucose levels are high
The liver releases insulin.
The pancreas releases insulin.
The liver releases glucagon.
The pancreas releases glucose.
The pancreas releases glucagon.
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The pancreas releases insulin
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A liver cell responds to insulin by
Taking in glucose and converting it to glucagon.
Releasing insulin.
Releasing glucagon.
Taking in glucose and converting it to glycogen.
Breaking down glycogen and releasing glucose.
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Taking in glucose and converting it to glycogen
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What cells in the body respond to glucagon by breaking down glycogen and releasing glucose?
Cells in the pancreas.
Muscle cells.
Liver cells and cells in the pancreas.
Liver cells.
Intestinal cells.
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Liver cells
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Body cells that respond to insulin include
Liver cells only.
Liver cells and muscle cells only.
Muscle cells only.
Liver cells, as well as most other cells of the body.
Intestinal cells only.
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Liver cells, as well as most other cells of the body
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When blood glucose levels are low
A.The pancreas releases glucagon, which eventually causes blood glucose levels to increase.
B.The pancreas releases insulin, which eventually causes blood glucose levels to increase.
C.Liver cells convert more glucose to glycogen.
D.The pancreas releases insulin, which eventually causes blood glucose levels to decrease.
E.The pancreas releases glucagon, which eventually causes blood glucose levels to decrease.
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A
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The body's tendency to maintain relatively constant internal conditions is called
homeostasis.
diabetes.
positive feedback.
negative feedback.
None of the above.
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Homeostasis
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What are the events that occur in your body after you eat a sugary snack.
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Blood glucose becomes high
-Pancreas releases insulin
Insulin binds to receptors on target cells
-Cells take in glucose
Blood glucose returns to normal
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Which of the following would activate secretion of a hormone from this gland?
A fall in the blood glucose concentration
A fall in blood calcium concentration
A rise in blood sodium concentration
Ingestion of excess water
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A fall in blood glucose concentration
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A rise in blood glucose level will trigger all these responses except __________.
storage of triglycerides
storage of glycogen
increased beta cell secretion
increased epinephrine secretion
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Increased epinephrine secretion
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Which of these is not produced by pancreatic islet cells?
digestive enzymes
somatostatin
insulin
glucagon
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Digestive ezymes
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Which cells are correctly matched to the hormones they produce?
alpha cells; insulin
acinar cells; insulin
beta cells; insulin
beta cells; glucagon
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beta cells; insulin
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Which of the following is NOT involved in elevating blood calcium concentration?
Parathyroid hormone
Calcitriol
Calcitonin
Vitamin D (cholecalciferol)
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Calcitonin
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Which of these is not a steroid hormone produced by the gonads?
progesterone
testosterone
cortisol
estradiol
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cortisol
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Adipose cells produce a hormone called __________ that acts on the brain to reduce food intake.
adipin
renin
leptin
insulin
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leptin
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Which of these statements about the resistance phase of the general adaptation syndrome is not true?
The dominant hormones are glucocorticoids.
It follows the alarm phase.
It precedes the exhaustion phase.
The dominant hormone is epinephrine.
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The dominant hormone is epinephrine
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Which of these hormones is required for normal growth?
thyroid hormone
insulin
growth hormone
All of these hormones are required for normal growth.
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All of these
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Calcitonin is secreted by which cells?
beta cells in the pancreas
C cells (parafollicular cells) in the thyroid gland
chromaffin cells
chief cells of the parathyroid gland
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C cells
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The sympathetic nervous system directly stimulates which of the following amine hormones?
insulin
thyroid hormones
aldosterone
epinephrine from the adrenal medulla
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epinephrine from the adrenal medulla
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What hormone causes the loss of sodium and water, thus lowering blood pressure.
atrial natriuretic peptide (ANP)
angiotensin II
erythropoietin
aldosterone
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Atrial natriuretic peptide (ANP)
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What amine hormone helps coordinate body activities with the light-dark cycle?
thymosin
inhibin
melatonin
prolactin
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Melatonin
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What hormone promotes glycogen synthesis in liver and muscle?
glucagon
insulin
epinephrine
cortisol
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Insulin
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Where is thyroid stimulating hormone (TSH) synthesized?
thyroid
anterior pituitary
posterior pituitary
adrenal cortex
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Anterior pituitary