question

You're about to administer cisplatin to a patient who has ovarian cancer. Before beginning the infusion, you should take which of the following actions? (Select all that apply.) Infuse 1 to 2 L of IV fluid. Check the patient's peripheral pulses. Administer an antiemetic. Evaluate the patient's hearing. Determine the patient's weight.

answer

Infuse 1 to 2 L of IV fluid. Administer an antiemetic. Evaluate the patient's hearing. Determine the patient's weight.

question

A patient is about to start taking mercaptopurine (Purinethol) to treat acute lymphocytic leukemia. You should instruct the patient to watch for and report which of the following indications of an adverse effect of this drug? Bruising Paresthesias Blurred vision Tinnitus

answer

Bruising

question

A patient is about to start therapy with topotecan (Hycamtin) to treat metastatic ovarian cancer. To minimize neutropenia, an adverse effect of topotecan, you should administer filgrastim (Neupogen) at which of the following times? 24 hr before the topotecan infusion At the same time as the topotecan infusion 24 hr after the topotecan infusion 1 hr before the topetecan infusion

answer

24 hr after the topotecan infusion

question

Match the drug in the left column with its therapeutic use in the right column by typing the appropriate letter in the center column. Tamoxifen (Soltamox) A. Advanced or resistant HIV disease Enfuvirtide (Fuzeon) B. Estrogen-receptor-positive breast cancer Delavirdine (Rescriptor) C. Prostate cancer Flutamide D. HIV-1 infection

answer

Tamoxifen, an estrogen receptor blocker, palliates estrogen-receptor-positive breast cancer for postmenopausal women and is an adjunct to surgery for breast cancer with positive lymph nodes. Enfuvirtide, an entry/infusion inhibitor, treats HIV infection that is advanced or resists treatment with other drugs. Delavirdine, a non-nucleoside reverse transcriptase inhibitor, treats the symptoms of HIV-1 infection. Flutamide, an androgen receptor blocker, treats early and metastatic prostate cancer.

question

You're assessing a patient who is receiving imatinib (Gleevec) to treat chronic myeloid leukemia. Which of the following findings may indicate an adverse reaction to this drug? Bradycardia Dry mouth Constricted pupils Crackles at lung bases

answer

Crackles at lung bases

question

While administering trastuzumab (Herceptin) IV to a patient who has breast cancer, you should ensure that you have which of the following drugs available to treat an adverse reaction to this drug? Protamine Epinephrine Glucagon (GlucaGen) Atropine

answer

Epinephrine

question

You're caring for a patient who is pregnant and is HIV-positive. Which of the following drugs helps prevent the transfer of HIV to the fetus? Anastrozole Zidovudine (Retrovir) Tamoxifen (Soltamox) Trastuzumab (Herceptin)

answer

Zidovudine (Retrovir)

question

A patient is about to start taking ritonavir (Norvir) to treat HIV-1 infection. Which of the following instructions should you include when talking with the patient about taking this drug? (Select all that apply.) Expect periodic blood glucose testing. Take it on an empty stomach. Watch for and report jaundice. Increase weight-bearing activity. Expect periodic cholesterol testing.

answer

Expect periodic blood glucose testing. Watch for and report jaundice. Increase weight-bearing activity. Expect periodic cholesterol testing.

question

Match the drug in the left column with its therapeutic use in the right column by typing the appropriate letter in the center column. Paclitaxel (Taxol) A. Multiple myeloma Cytarabine (Cytosar-U) B. Gastrointestinal adenocarcinoma Cyclophosphamide C. Kaposi's sarcoma Carmustine (BiCNU, Gliadel) D. Acute myelocytic leukemia

answer

Paclitaxel, an antimitotic, treats Kaposi's sarcoma, ovarian and breast cancer, and non-small cell lung cancer. Cytarabine, an antimetabolite (pyrimidine analog), treats acute myelocytic and acute lymphocytic leukemia and non-Hodgkin's lymphoma. Cyclophosphamide, an alkylating agent (nitrogen mustard), treats leukemia; multiple myeloma; lymphomas; and head, ovary, breast, and lung cancer. Carmustine, an alkylating agent (nitrosourea), treats brain tumors, lymphomas, multiple myeloma, melanoma, hepatoma, and gastrointestinal adenocarcinoma.

question

You should instruct a patient who is taking tamoxifen (Soltamox) to treat breast cancer to watch for and report which of the following serious adverse effects of this drug? Abnormal menstrual bleeding Muscle pain and weakness Yellowing of skin and eyes Peripheral edema

answer

Abnormal menstrual bleeding

question

You're administering cyclophosphamide and mesna (Mesnex) to a patient. Mesna, a chemoprotective agent, helps prevent which of the following adverse reactions to cyclophosphamide? Retinopathy Seizure activity Hemorrhagic cystitis Cardiotoxicity

answer

Hemorrhagic cystitis

question

You should monitor this patient for which of the following indications of an adverse reaction to cyclophosphamide? Gynecomastia Dilated pupils Bradycardia Fever

answer

Fever

question

When talking with the patient about chemotherapy with doxorubicin (Adriamycin), you explain the need for periodic diagnostic tests. The result of which of the following diagnostic tests or procedures requires monitoring? Lumbar puncture IV pyelogram Bone density scan ECG

answer

ECG

question

You should give the patient which of the following instructions about chemotherapy with doxorubicin (Adriamycin)? (Select all that apply.) Report vaginal itching. Expect red-tinged tears. Use effective contraception. Expect regrowth after hair loss. Increase intake of calcium and vitamin D.

answer

Report vaginal itching. Expect red-tinged tears. Use effective contraception. Expect regrowth after hair loss.

question

During IV administration of doxorubicin (Adriamycin), the infusion site becomes swollen, red, and painful. Which of the following actions should you take? Slow the infusion rate. Apply pressure to the site. Stop the IV infusion. Apply ice and continue the infusion.

answer

Stop the IV infusion.

question

When caring for a patient who is receiving vincristine, a vinca alkaloid to treat lung cancer, the health care professional should monitor for which of the following findings that indicate an adverse effect? Weak hand grasps Constricted pupils Bradycardia Crackles

answer

Weak hand grasps

question

A health care professional is about to administer enfuvirtide (Fuzeon), a fusion inhibitor, to a patient. The health care professional should perform which of the following actions? Administer the drug subcutaneously Discard unused portion Roll the vial gently to reconstitute the solution Inject the solution at room temp Expect a cloudy solution

answer

Administer the drug subcutaneously Roll the vial gently to reconstitute the solution Inject the solution at room temp

question

A health care professional should understand that raltegravir (Isentress), an integrate inhibitor, treats patients who have which of the following? Hairy cell leukemia Thyroid cancer Kaposi's sarcoma Resistant HIV disease

answer

Resistant HIV disease

question

While assessing a patient who is receiving interferon alfa-2a (Roferon-A) to treat Kaposi's sarcoma, the health care professional should check for which of the following possible indications of an adverse reaction? Bradycardia Dilated pupils Fever Constipation

answer

Fever

question

A health care professional is caring for a patient who is about to begin intrathecal cytarabine (DepoCyt) therapy to treat meningeal leukemia. The health care professional should explain that the patient should also receive which of the following drugs to reduce the risk of neurotoxicity? Diphenhydramine Leucovorin Folic acid Dexamethasone

answer

Dexamethasone

question

A health care professional is caring for a patient who is about to begin receiving cisplatin, a platinum compound, to treat testicular cancer. The health care professional should tell the patient to report which of the following adverse effects? Paresthesias Sore throat Flank pain Tinnitus Conjunctivitis

answer

Paresthesias Sore throat Flank pain Tinnitus

question

A health care professional is caring for a patient who is about to begin delavirdine (Rescriptor) therapy to treat HIV-1. The health care professional should tell the patient to report which of the following adverse reactions to the drug? Rash Insomnia Rhinitis Alopecia

answer

Rash

question

A health care professional is caring for a patient who is receiving IV carmustine (BiCNU), a nitrosourea drug, to treat multiple myeloma. The health care professional should recognize that the patient is at the greatest risk for infection for which of the following lengths of time after the infusion? 24 hr 1 week 2 weeks 4-6 weeks

answer

4-6 weeks

question

A health care professional is assessing a patient following a trastuzumab (Herceptin), a monoclonal antibody, infusion to treat metastatic breast cancer. Which of the following findings indicates an adverse reaction to the drug? Wheezing Dysrhythmias Hypotension Fever Ascites

answer

Wheezing Dysrhythmias Hypotension Fever

question

A health care professional is caring for a patient who is about to begin taking mercaptopurine (Purinethol), a purine analog, to treat leukemia. Which of the following instructions should the health care professional include when talking with the patient about the drug? Use contraception if pregnancy is a risk Perform oral hygiene frequently Avoid activities that require mental alertness Perform hand hygiene frequently Avoid activities that can cause injury

answer

Use contraception if pregnancy is a risk Perform oral hygiene frequently Perform hand hygiene frequently Avoid activities that can cause injury

question

A health care professional should question the use of anastrozole (Armidix), a aromatase inhibitor, for a patient who is allergic to salicylates premenopausal hearing impaired immunocompromised

answer

premenopausal

question

When talking to a patient who is about to begin vincristine therapy to treat lymphoma, the healthcare professional should include which of the following instructions? Increase fiber intake Report tinnitus or vertigo Take the drug with 8 oz of water Allow 4 hr before taking an antacid

answer

Increase fiber intake

question

When caring for a patient who is taking flutamide to treat prostate cancer, the health care professional should monitor the patient for which of the following adverse effects of the drug? Dehydration Gynecomastia Constipation Tachycardia

answer

Gynecomastia

question

A health care professional is caring for a patient who is about to begin maraviroc (Selzentry) therapy. The health care professional should tell the patient to report which of the following adverse effects of the drug? (Select all that apply) Paresthesias Cough Tinnitus Jaundice Fever

answer

Paresthesias Cough Jaundice Fever

question

A health care professional is caring for a patient who is about to start ritonavir (Norvir) and zidovudine (Retrovir) therapy to treat HIV-1. The health care professional should explain that the patient will receive ritonair along with at least once reverse transcriptase inhibitor to Prevent an infusion reaction Increase platelet production Protect healthy cells from the toxic effects of ritonavir Prevent drug resistance

answer

Prevent drug resistance

question

A health care professional is about to administer IV paclitaxel (Taxol), an anti mitotic drug, to a patient who has ovarian cancer. Which of the following actions should the health care professional take? Give the patient an antihistamine Infuse the drug over 1 hr Administer the drug through non-PVC tubing Use an in-line filter Add heparin to the paclitaxel solution

answer

Give the patient an antihistamine Administer the drug through non-PVC tubing Use an in-line filter

question

A health care professional is caring for a patient who is about to begin topotecan (Hycamtin), a topoisomerase inhibitor, therapy to treat resistant, small-cell lung cancer. The health care professional should caution the patient about taking which of the following types of over-the-counter drugs while receiving the therapy? Folic acid St. John's Wort Ibuprofen (Advil) Aluminum hydroxide (Amphojel)

answer

Ibuprofen (Advil)

question

A health care professional should question the use of maraviroc (Selzentry) for a patient who has which of the following? DM Meningeal infection Pancreatitis Non-chemokine receptor 5 (CCR5)-tropic HIV-1

answer

Non-chemokine receptor 5 (CCR5)-tropic HIV-1

question

A health care professional should question the use of cyclophosphamide, a nitrogen mustard, for a patient who has which of the following? Raynaud's syndrome Dehydration Jaundice Charcot-Marie-Tooth Syndrome

answer

Dehydration

question

When talking with a patient who is about to begin methotrexate (Trexall), a folic acid antagonist, therapy to treat non-Hodgkin lymphoma, the health care professional should include which of the following instructions? Take echinacea supplements Use a soft-bristled toothbrush Take aspirin to reduce muscle pain Urinate Q 4 hr

answer

Use a soft-bristled toothbrush

question

A health care professional is caring for a patient who is about to begin imatinib (Gleevac), a targeted antineoplastic drug, to treat chronic myeloid leukemia. Which of the following instructions should the health care professional include when talking to the patient about taking the drug? Clean fruits and vegetables thoroughly Increase calcium intake Weight yourself daily Perform hand hygiene frequently Avoid herbal supplements

answer

Clean fruits and vegetables thoroughly Weight yourself daily Perform hand hygiene frequently Avoid herbal supplements

question

A health care professional is caring for a patient who is about to begin taking tamoxifen (Soltamox), an estrogen-receptor blocker, to treat breast cancer. The health care professional should recognize the need for cautious use of the drug if the patient also has which of the following? Cataracts COPD DM Alcohol use disorder

answer

Cataracts

question

When considering drug therapy options for a patient who has metastatic breast cancer that is positive for human epidermal growth factor receptor 2 (HER2), the health care professional should choose which of the following drugs? Trastuzumab (Herceptin) Imaatinib (Gleevec) Leuprolide (Lupron) Flutamide

answer

Trastuzumab (Herceptin)

question

Unless there are any specific contraindications, which of the following immunizations should adults receive once each year? Varicella Tetanus Influenza Hepatitis B

answer

Influenza

question

A health care professional should understand that enfuvirtide (Fuzeon) is an appropriate choice for patients who have which of the following? Advanced prostate cancer Primary brain tumors Advanced HIV disease Metastatic ovarian cancer

answer

Advanced HIV disease

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