5th – Flashcards
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erection, contraction of smooth muscle of bladder wall, and increased motility of digestive organs
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Effects caused by stimulation of the parasympathetic division include __________.
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sweat glands, arrector pili muscles, and adipose tissue
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Which of these organs/tissues are NOT innervated by parasympathetic fibers, or do not exhibit parasympathetic effects?
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Focusing the eye on a nearby object in the field of vision is a function of which division of the ANS?
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parasympathetic
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vagus
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Which of the following cranial nerves does not supply parasympathetic fibers to the head?
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ciliary muscle of the eye
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Which one of these is solely innervated by the parasympathetic division?
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thoracolumbar region, and the postganglionic fibers secrete norepinephrine.
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Sympathetic fibers leave the spinal cord in the
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modified postganglionic neurons in the medulla secrete epinephrine and norepinephrine, which act as blood-borne neurohormones, rather than as neurotransmitters
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The adrenal medulla is different from the remainder of the sympathetic division because __________.
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inhibit lacrimal, salivary, and nasal secretions
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Functionally, sympathetic postganglionic axons of the head and neck relay impulses to glands, smooth muscle, and vessels of the head that __________.
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White rami carry the preganglionic sympathetic outflow from the spinal cord.
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Why are white rami communicantes found only in the region of T1â€"L2?
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sympathetic
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Which division of the nervous system is characterized by highly branched postganglionic fibers that innervate multiple organs?
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Increased blood pressure and heart rate
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A person who is stressed out, usually has an overactive sympathetic nervous system. What would be some of the symptoms of stress-induced hypertension?
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hypothalamus
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The overall integrating center for the ANS.
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sa Dilation ps Constriction/contraction
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Eye: pupil/ciliary muscle
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Vasoconstriction (s) Secretion P
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Lacrimal gland
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Scanty, thick secretion (s) Copious thin secretion (p)
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Salivary gland
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Increased rate and force of contraction s Slowed rate p
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Heart
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Decreased peristalsis and secretion s Increased peristalsis and secretion p
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Gut
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Vasoconstriction s Vasodilation p
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Lungs: bronchi
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simplest of endocrine control mechanisms
Secretion in direct response to changing ion or nutrient levels in the blood
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Humoral
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Inhibits urination s Contraction p
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Bladder detrusor (muscle)
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Ejaculation s Erection p
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Penis
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Secretion s
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Adrenal medulla
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Vasoconstriction, sweat secretion, pilo-arrection s
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Skin of head, neck, and extremities
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Neural - secretion of endocrine glands controlled by neural stimuli
Example: sympathetic nerve fibers stimulate cells in the adrenal medulla. Induces release of epinephrine and norepinephrine
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Neural
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Hormonal - stimuli received from other glands
Certain hormones signal secretion of other hormones
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Hormonal
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Must bind to receptor on the target cell membrane and trigger second messengers
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amino acids
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Can go across cell/nuclear membrane to bind receptor
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sterroids
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anterior pitutitary grandular tissue
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Adenohypophysis
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(posterior)- neural tissue; part of the brain- pituitary
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Neurohypophysis
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-regulate hormone secretion of other endocrine glands - hormonal stimulation
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Tropic hormones-
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thyriod from: Adenohypophysis
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Thyroid stimulating hormone (TSH) target?
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signals thyroid to release (TH) from: Adenohypophysis
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signals thyroid to secrete TH effect?
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signals adrenal cortex to release stress hormones
from: Adenohypophysis
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Adrenocorticotropic hormone (ACTH) effect?
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adrenal cortex from: Adenohypophysis
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Adrenocorticotropic hormone (ACTH) target?
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gonads from: Adenohypophysis
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Follicle-stimulating hormone (FSH) target
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maturation of soperm and e.g.g from: Adenohypophysis
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Follicle-stimulating hormone (FSH) effect?
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body growth from: Adenohypophysis
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Growth Hormone (GH) (a.k.a. somatotropic hormone effect
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body cells from: Adenohypophysis
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Growth Hormone (GH) (a.k.a. somatotropic hormone target
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effect: milk production target: mammary gland from: Adenohypophysisfrom:
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Prolactin
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unmyelinated axons
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Hypothalamohypophyseal tract contains?
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does not make hormones
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Neurohypophysis
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Antidiuretic hormone and Oxytocin
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Neurohypophysis - what hormones does this secrete
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uterous and mammary gland
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Oxytocin target
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uterine contraction and milk secretion
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Oxytocin effect?
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kidneys and arterioles
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Antidiuretic hormone target
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Antidiuretic hormone
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alchol inhibits this
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negative
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Antidiuretic hormone what kind of feedback loops
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positive
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Oxytocin what kind of feedback loops
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Largest pure endocrine gland
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The Thyroid Gland
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person always cold, gains weight but doesn't feel hungry.
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Hypothyroidism
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lack of iodine
Hypothyroidism
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Goiter
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Person is "hot", loses weight, very hungry, anxious.
Graves' disease ( autoimmune - t cells start to attack normal body cells
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Hyperthyroidism
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Adrenal medulla
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Chromaffin cells are foudn where
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a knot of sympathetic nervous tissue
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Adrenal medulla
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modified postganglionic sympathetic neurons
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Chromaffin cells
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Secrete (amino acids) norepinephrine and epinephrine
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Chromaffin cells secrete what?
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Active in "fight, flight, and fright" response
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Chromaffin cells are active in what
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secreted by zona fasciculata and zona reticularis in response to ACTH
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Cortisol secreted by what
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stimulates fat and protein catabolism and gluconeogenesis.
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Cortisol effect
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Glucocorticoids
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cortisol is what class
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Mineralocorticoids
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Aldosterone is what class
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zona glomerulosa
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Aldosterone secreted by what
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Sodium/water reabsorbed to maintain blood volume and pressure.
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Aldosterone target?
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Contains both endocrine and exocrine cells
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the pancrease contains
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acinar cells - secrete digestive enzymes into small intestine
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exocrine cells of pancrease
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pancreatic islets (islets of Langerhans) contains both α and β cells
About one million islets - scattered throughout the pancreas
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endocrine cells of pancreas
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Beta cells (β cells-70%) - secrete insulin
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Main endocrine cell type
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Signals most body cells to take up glucose from the blood
Lowers blood suga
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insulin
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Alpha cells (α cells-20%)
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2nd most pancreatuc cells
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target: liver efffecgt: raising blood sugar secrete glucagon
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Alpha cells (α cells-20%)
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T cell-mediated autoimmune response destroys beta cells
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Type I diabetes
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Exocrine: produce sperm
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testes exocine
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Endocrine: produce gonadal hormones (steroids)
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testes endo
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Promotes the formation of sperm
Maintains secondary sex characteristics
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testosterone
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Both exocrine and endocrine
Exocrine: produce eggs
Endocrine: produce gonadal hormones (steroids)
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Female/ Ovaries
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maintains secondary sex characteristics and signals uterine mucosa to repair itself after menstrual period
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Estrogen
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prepares the uterus for pregnancy
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Progesterone
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enteroendocrine cells, scattered within the epithelial lining of the alimentary canal. Assist with digestion, blood chemistry, etc.
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The GI tract
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stomach to secrete HCl from gi tract target is the stomach effect secreation of hydrochloric acid
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Gastrin
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cck gallbladder to release bile target gull bladder effect tis to trellis bile
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Cholecystokinin
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sustains the fetus and secretes several steroid and protein hormones -maintain and sustain the fetus p from the point of conception
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The placenta
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hormone - thymic hormones - target t cells - maturation of these t cells
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thymus gland
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pregnancy tests
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Human chorionic gonadotropin- HCG
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erythropoietin epo (bone marrow produces RBC);
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kidneys produce
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More of that hormone is secreted, which prompts further secretion of that hormone.
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In a positive feedback loop, if concentrations of a specific hormone increase, what is the response of the effector organ?
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adrenal
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Identify the letter that indicates a gland that secretes corticosteroids.
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hormona
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The major stimulus for the release of thyroid hormone is
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nervous.
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The major stimulus for the release of the amine hormones of the adrenal gland is
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posterior lobe of the pituitary and adrenal medullae
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Which of the purely endocrine organs contain modified neurons that produce and secrete neurohormones?
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cholesterol
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Steroid hormones are molecules that are derived from __________.
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Releasing hormones produced and secreted in the hypothalamus stimulate secretion of anterior lobe hormones.
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What stimulates the secretion of anterior lobe hormones from the pituitary?
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Hypothalamic neurons stimulate the release of stored hormones from their axon terminals located in the posterior lobe.
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What stimulates the secretion of posterior lobe hormones from the pituitary?
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kidney
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Which organ is influenced by antidiuretic hormone (ADH)?
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medulla
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Which portion of the adrenal gland secretes hormones in response to "fight-or-flight" situations?
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tropic
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Four of the seven hormones secreted by the pars distalis regulate the secretion of other endocrine glands. These four hormones are called__________ hormones.
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neurohypophysis
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The pars nervosa and infundibular stalk are both part of the__________ .
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thyroid hormone
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If a patient's basal metabolic rate (BMR) is always low, which hormone is not functioning correctly?
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MSH
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Which of the following hormones secreted by the pars distalis does not regulate the function of other endocrine glands?
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the pineal gland
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Which endocrine gland stands out in X-ray images and helps radiologists get oriented in the brain?
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the gonads
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The target of follicle-stimulating hormone (FSH) is
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Which of the following is/are true of aldosterone?
It is a steroid hormone.
It compensates for a decline in blood pressure or blood volume by prompting the distal convoluted tubules and collecting ducts of the kidneys to resorb more sodium into the blood.
It is secreted in response to a decline in blood volume or blood pressure.
It is secreted by the zona glomerulosa of the adrenal cortex.
All statements listed are true of aldosterone.
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Which of the following is/are true of aldosterone?
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axons from the medial half of each eye
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What axons decussate in the optic chiasma?
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lens
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Clouding of which of the following structures would lead to a clinical condition known as a cataract?
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levator palpebrae superioris.
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The muscle that opens the eye is the
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facial
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Which cranial nerve does not innervate the extrinsic eye muscles?
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dilator/sphincter pupillae muscles
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Which of the following controls the amount of light entering the eye?
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oval window
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Membrane attached to the stapes
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vestibule
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Bony labyrinth structure containing the utricle and saccule.
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otoliths
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Calcium carbonate crystals of the macula.
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cochlear duct
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Endolymph-filled structure containing receptors for hearing.
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tectorial membrane
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Gel-like structure embedded with the tips of cochlear hair cells.
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air.
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The middle ear cavity is normally filled with
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peterous part
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The bony labyrinth is located in which portion of the temporal bone?
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semicircular ducts.
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The cristae ampullares in the inner ear are located in the
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The affected eye is turned medially or laterally with respect to the normal eye; results from weakness or paralysis of extrinsic eye muscles.
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What is strabismus
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utricle
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Along with the saccule, this structure senses linear acceleration.
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terminates at the round window at the base of the cochlea and is filled with perilymph
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The scala tympani __________.
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The tensor tympani and stapedius muscles contract reflexively.
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You are listening to music on your iPod at a very loud volume. What happens in your middle ear to protect the hearing receptors in your inner ear?
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equalizes air pressure
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Pharyngotympanic/ eustachian tube/ auditory tube
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calcitonin
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Hormone that inhibits osteoclast activity in children
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parafollicular cells
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Cells of the thyroid that produce calcitonin.
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tropic
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Class of hormones that regulates secretions of other endocrine glands.
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colloid
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Jellylike substance found in the thyroid follicles containing high concentrations of stored thyroglobulin.
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iodine
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Which of the following minerals is essential for the formation of thyroid hormone?
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growth hormone-releasing hormone
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Which of the following hormones is secreted into the primary capillary plexus of the hypophyseal portal system?
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infundibulum.
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The hypophyseal portal veins are primarily located in the
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kidney
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Erythropoietin is produced in the
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gland: anterior putitary target: thyroid gland efects: signal thyroid to release thyroid hormone
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thyroid stimulating hormone (TSH)
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gland: anterior putitary target: adrenal cortex effect: secretion of stress hormone
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Adenocorticotropic hormone (ACTH)
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gland; anterior pituitary target: gonads efeects: maintain sperm and eggs
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follicle stimulating hormone (FSH)
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gland: anterior pituitary target: gonads effect: secrete sex hormone testosterone and estrogen
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lutenizing hormone (LH)
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gland: anterior pituitary target: body cells efefct: growth of body cells
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growth hormone (GH)
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gland: anteiror pit target: mammary gland efeects milk production
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prolactin
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glnd : at target: the skin effect : darkening of the skin
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melanocytestimulating hormone (MSH)
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gland pt target: kideys/arterides efect: fluid reabsorptioin and vasoconstriction
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antidiuretic hormone (ADH)
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gland PT target: uterus/mammary gland effect: uterues contraction and milk secretion
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oxytocin
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gland thyoid: target: body cells effects: control metabolic rate protien synthesis
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thyroid hormone (TH T4T3)
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gland thyoid: target: bones/kidneys effects: depresses bllod CA leves
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calcatonin
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target: bone/kidneys/GI tract (sm intestine) effect: raises blood Ca leves/stimulates osteoclast/decreases kideney secretion/activates vitamin d uptake
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parathyroid hormone (PTH)
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gland: pancrease target: liver efect: raises blood sugar
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glucagon (alpha cells )
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pancreas/liver/remove sugar from blood
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insuline (beta cells )
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adrenal/body cells/sugar for brain
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cortisol (glycocorticoids)
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adrenal cortex/kideys/sodium/water reabosorption
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aldosterone (mineralcoticoids)
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secondary sex characteristic
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testosterone
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ovaries/prepares uterus for preganacy
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proestergen
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t cell maturation t cells
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thymic hormones
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pineal gland/brain/ sleep cycles
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melatonion
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adrenal medula/body cells/flight or flight
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norepineporine
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gi tract/ stomach/ HCL production
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gastrin
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gallbladder/bile porduction
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cholecytokinin CCK
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preganacy
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human chronic gonadotyropin
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kidneys/bone marrow/RBC production
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erythroprotien EPO
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sclera and cornea; continuous with each other.
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Fibrous Tunic
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light enters here, transparent (most anterior aspect)
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Cornea
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Choroid Ciliary body Iris
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Vascular Layer
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forms posterior 5/6 of vascular tunic, continuous with ciliary body; prevents light scatter
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Choroid
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a thickened ring of tissue that encircles the lens- consists of smooth muscle (ciliary muscle) - focuses the lens.
Makes aqueous humor
Accomodation - buldge or strech
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Ciliary body
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isible, colored part of eye. Allows light to enter. Has smooth muscle fibers (sphincter-constriction/ parasympathetic and dilator- dilates /sympathetic)
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Iris
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constricts pupil/ parasympathetic
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sphincter pupilae
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dialates pupil/sympathetic
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dialator pupillae
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Pigmented layer, Neural layer
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layers of the retina
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deepest part
(Absorb light and prevent scatter)
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Pigmented layer
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(nervous tissue; external to internal) (thicker)
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Neural layer
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neural layer meets ciliary body
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Ora serrata
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where the fovea centralism sits
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Macula lutea
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only have cones
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Fovea centralis
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Transmits air vibrations to auditory ossicles
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Tympanic Membrane
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Round window Ossicles
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Middle Ear (tympanic cavity)
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malleus, incus, stapes (merge onto oval window)- transmit sound from external ear to internal ear.
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Ossicles
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dissipates left-over energy in cochlea Oval window (stapes)
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Round window
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equalizes air pressure
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Pharyngotympanic/ eustachian tube/ auditory tube-
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Reflexive muscles that protect from loud sounds (tympanic reflex)
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Stapedius (stapes)
Tensor tympani (malleus)
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senicircular canals, vestibule, cochlea
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bony labrynth
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sencircular ducts, utricle and saccule, cochlear ducts
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membranous labrynth
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hearing
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cochlear duct function
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equilibrium:static equalibrium adn linear acclereation of teh head
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urticle and saccule function
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equilibrium: rotational angulr acceleration of the head
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semicircular ducts
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Has special sensory epithelium called Macula
Receptor hair cells
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Utricle and Saccule
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Innervated by CN VIII (vestibular division)
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Utricle and Saccule
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calcium carbonate crystals
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Otoliths
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horizontal orientation
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Utricle
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vertical orientation
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Saccule
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responsible for "triggering" hair cells
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Otolithic membrane
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Crista ampullaris- (crest with hair cells)
Cupula- jelly-like pointed cap
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Ampulla
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what cochlea binds to
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Modiolus
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Scala vestibuli Scala tympani (
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Perilymph-filled chambers:
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cochlear duct
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Endolymph
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Hair cells- stereocilia
Supporting cells
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Organ of Corti