Review Intro to Anesthesia – Flashcards

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SAIL
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S = Septal V1 V2 : A = Anterior V3 V4 : LAD I = Inferior II III AvF : RCA L = Lateral I V5 V6 AvL : Circumflex
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Lead II
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Best lead for P wave monitoring Best for determining arrhythmias Inferior wall ischemia
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Pulse Oximeter
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Contains 2 LEDs Red (660nm) deoxy hemoglobin Infrared (940nm) oxyhgb Ratio of red to infrared light absorption during arterial pulsations estimates SaO2 by an empirical algorithm from healthy volunteers Accuracy is within 2-4% Accurate from 70% - 100% Ear pulse ox will show you the change the quickest
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Pulse Ox spurious readings
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Methylene blue will decrease the SpO2 - by interfering with the wave length and effecting the algorithm
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MetHgb
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From prilocaine or benzicaine Causes a falsely low saturation reading SpO2 is actually greater than 85% and a falsely high reading if SpO2 is actually less than 85% Tx give methylene blue
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CarboxyHgb
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From stroke, carbon monoxide Will decrease SpO2 overtime but the Pulse ox reading is false reads higher than actual PaO2 This cause by a shift left hgb holding onto O2 and not releasing it to the tissue
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Left Shift
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Hypothermia, Decreased 23 DPG, Increased PH --> Hypoactive
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Right Shift
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Hyperthermic, Decreased PH, Increased 23DPG --> Hyperactive (hyper metabolic)
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Capnography
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Indirect assessment of PaCO2 Gradient of 5-8 torr between the ETCO2 and the PaCO2 Due to alveolar dead space ETCO2 will always be lower than PCO2 (i.e. ETCO2 = 30 and PCO2 = 40 Normal sampling volume is 250ml/min from side stream
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SALT
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Suction Airway Laryngoscope (bright light: different blades) Tube (2 tubes: stylet: CHECK CUFF)
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V5
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A^2 or AA 5th intercostal space Most sensitive monitor for detection of anterior or lateral ischemia
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Based on Beer-Lambert's Law
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Pulse ox measurements are based on this principle Oxygenation and Deoxygenated hgb differ in absorption of red and in fared light
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Limitations of the Pulse Ox
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Requires pulsating arterial bed Low perfusion states does not work Cold (vasoconstriction) Dyes (methylene blue or Indigo carmine) = as soon as circulated pulse ox will give a false low reading lasts about 3m Electrocautery/motion Intense light Requires Hgb (severe anemia) Requires nonpulsitile venous bed
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Malignant hypothermia
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More common in children Hyermetabolic state with a high production of CO2 = ETCO2 will climb quick and fast (Increased temp is a late sign) TX: with dantrolene Stop triggers: Succs or inhalation agent
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Capnography waveform: Phase 1
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Flat Should be at zero Inspiration Devoid of CO2 Anatomic deadspace Apparatus deadspace
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Capnography waveform: Phase II
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Early point of exhalation Sharp upstroke = normally near vertical Represents appearance of expired CO2 Signifies the mixing of deadspace gas with alveolar gas
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Capnography waveform: Phase III
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Plateau capnography normally horizontal may have slight incline Represents CO2 rich alveolar air Most Physiology Airway resistance End plateau point is the ETCO2 Best clinical reflection of alveolar CO2 tension
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Capnography waveform: Phase 4
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Rapid downstroke Corresponds to fresh gas sampled with inspiration Travels back to baseline Should be zero Unless rebreathing has occurred
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Abnormalities: Phase 1
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Above baseline CO2 in inspired gas (rebreathing) Very small and rapid tidal volume Expiratory value incompetent CO2 absorber used up, low gas flow (dial flows up to decrease rebreathing)
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Abnormalities: Phase 2
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Slanted upstroke Partial obstruction Slow sampling rate Slow respond time
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Abnormalities: Phase 3
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Slanted upstroke Airway resistance Low resistance first then high resistance Biphasic waveform
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Abnormalities: Phase 4
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Oscillations in down slope = diaphragm moving after NMB Incompetent inspiratory valve reverse flow alarm Cuff Leak
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Increased ETCO2
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Hypoventilation Increased metabolic states MH, Sepsis, thyrotoxicity Rebreathing Tourniquet release (transient: lactic acid build up = a drop in BP as the limb refills = inc ETCO2) Administration BiCarb Insufflation during laparoscopy: blow belly up with CO2 (decrease TV inc rate) Exhausted soda lime
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Decreased ETCO2
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Hypothermia = dec CO2 production Decreased CO2 = decrease delivery to the lungs Hyperventilation Pulmonary embolus Leak in system
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Agent Analyzer
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Monitor various gases: N2, N2O, O2 and anesthetic agents Assessment of anesthetic delivered = detection of toxic concentrations O2 consumption = difference between inspired to expired O2
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Hypothermic Effects
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Ventricular arrhythmias <28 - 30 C Increased peripheral vascular resistance Left shift of Hgb-oxygen saturation curve (hgb holds O2 and does not release to tissue) Decreased drug metab
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Postoperative effects of low temperature
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Shivering Increases O2 consumption 300-400% Decreases SpO2 Increases risk of MI Protein catabolism/stress response Altered mental status Impaired renal function Poor wound healing
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Nerve Stimulators
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Place electrodes over course of nerve not the muscle Ulnar nerve stimulation (adductor pollicis muscle) = more accurate Facial nerve stimulator (orbicular is oculi muscle) = comes back quicker
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TOF
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4 successive twitches in 2 seconds Twitches fade as relaxation increases 3 or 4 twitches = 75% blockade 2 twitches = 80% blockade 1 twitches = 90% blockade (must have at least 1 twitch to reverse) 0 twitches = 100% blockade (cannot reverse)
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Best Test for Recovery
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Head lift 5 secs: laryngeal muscles and pt cooperation and understanding Hand grasp 30-50 % what they were previously
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BIS
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Computer processed EEG : uses scalp electrodes Reflects anesthetic effects on the CNS : good for the correct titration of anesthetic agents 0: death 45-60: surgical anesthetic ( bis is good here) want pt at 60 80-95: sedated 100: fully conscious
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Monitored Anesthesia Care
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Sedation with no loss of consciousness or protective reflexes Pre-anesthesia evaluation Prescription of anesthetic care Administration of medication Post-op anesthesia care
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MAC for Which Procedure
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Any procedure in which local infiltration is likely to provide adequate surgical anesthesia Cystoscopy Suction D&C = as long as they are <10wks Eye Procedures Thrombectomy/AV GraftBreast Biopsy
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Lidocaine
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Plain: 4mg/kg With Epi: 7mg/kg Total: 300 mg
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Bupivicaine (Marcaine)
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Plain: 3 mg/kg With Epi: mg/kg Total: 175 mg
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Addition of Epi to Local
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Not recommended with: Unstable angina Arrhythmias Ureteroplacental insufficiency Uncontrolled HTN IV regional anesthetic Areas that may lack collateral flow Penis Digits Ear lobes/Nose
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Local Anesthetic Toxicity
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Dysphoric feeling Ringing or roaring in the ears Metallic taste in mouth Circumoral numbness Slurred speech Drowsiness Small muscle twitching (face/hands) Arrhythmias Seizures Hypotension Cardiac arrest Make sure pt has on O2 = increases seizure threshold
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Pre-seizure CNS symptoms
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50-100mg Sodiumthyopentathol Increases seizure threshold Seizures CAll for help Oxygenate, Hyperventilate Decreasing PaCO2 decreases cerebral blood flow and thus decreases delivery of local to the brain Check BP, Pulse Succs = stops peripheral manifestations of seizure
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Our Job
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Provide "Twilight Sleep" With pt 100% of the time Monitor VS, oxygenation Consider some form of CO2 monitor Either nasal prongs with CO2 port or CO2 tubing held down by mask Make them very sleepy for LA injection: after they may doze off and on If we can't get pt comfortable we induce general anesthesia *Normal MAC sleeping but arousable*
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Midazolam (Versed)
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...
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Fentanyl
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...
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STP or Brevital
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...
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Propofol
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...
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Obstruction
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Rocking motion of the chest wall Attempt to move air, but posterior wall of pharynx is obstructed by tongue or epiglottis (head tilt/chin lift) Usually occurs after anesthetic induced relaxation of pharyngeal-laryngeal muscles Exaggerated in edentulous pt #1 Stimulate #2 Chin lift/jaw thrust #3 Nasal airway
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Nasal Airway
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For semiconscious For lightly sedated anesthetized pt Must be lubricated Avoid in children or anti coagulated patients (prominent adenoids could cause bleeding)
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Oral Airway
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Used to maintain potency of pharynx in unconscious patients Correct length = distance from the tip of the nose to the ear lobe
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Laryngospasm
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Spasm of the laryngeal musculature (upper airway) Results in the closure of vocal cords and inability to ventilate Caused by: Secretions Noxious stimulation during light plane of anesthesia Treatment Call for help 100% O2 Apply 15-20cmH2O continuous airway pressure If persistent spasms and hypoxia develops give SUCCS = 20mg up to full dose
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Negative pressure pulmonary edema
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YOUNG STRONG MEN = they try to breath hard against a closed glottis = they will have a low O2 sat and extra secretions
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Bronchospasm
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Lower airway obstruction Manifested by involuntary contraction of the bronchial portion of respiratory tree May have wheezing Treatment: Deepen anesthesia Beta agonist Proventil inhaler (albuterol) Epi (SQ/IV) Steroids Aminophylline
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Mallampati Class 1
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Full visibility of tonsils, uvula and soft palate
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Mallampati Class 2
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Visibility of hard and soft palate, upper portion of tonsils and uvula
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Mallampati Class 3
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Soft and hard palate and base of the uvula are visible
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Mallampati Class 4
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Only Hard Palate visible
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NPO Status
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Clears - 2 hours Breast milk - 4 hours Formula/milk - 6 hours Light meal - 6 hours
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Cardiovascular
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Operative hx (CABG, CEA, etc) Medical hx: s/p MI, CAD , HTN, CHF, rheumatic fever, MVP, murmur/valve problem = medications often provide clues Symptoms: chest pain/pressure, arrhytmias, DOE, PND; progression of symptoms Exercise tolerance: stairs, walking/shopping, etc PVD history and symptoms
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Pulmonary
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COPD, asthma: cause frequency last time in ER? Previous chest surgery SOB: progression of symptoms, wheezing, stridor, sleeping position? Medications Recent URI: any current symptoms, differentiate between head cold/chest congestion
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Renal
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Especially important with DM CRI/CRF: dialysis, how long? When was last HD? Post - transplant S/P Nephrectomy
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Hepatic/GI
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Jaundice, cirrhosis Hepatitis history: when? cause? look at LFT PUD, chronic heartburn Reflux symptoms Hiatal hernia: Symptomatic? Can they sleep flat? Meds? Recent N/V?
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Neurological
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History of HA Syncope/seizure TIA's, visual disturbances CVA history: existing parasthesia, paralysis? Other focal neuro signs IMPORTANT AREA TO FOCUS ON FOR REGIONAL ANESTHETIC
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Endocrine/Metabolic
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DM (IDDM vs NIDM): duration? brittle? Medication: give 1/2 insulin dose after IV started: Hold ORAL HYPOGLYCEMICS Other endo problems: Thyroid/parathyroid, pituitary, adrenal/PHEO, morbid obesity
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Musculoskeletal
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MS Hemiparesis Arthritis Whiplash Hx Broken bones Lower back pain
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Psychiatric
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Dep/anx Schizophrenia Alzheimer's Dementia Meds : Prozac/SSRIs, MAOI, Trcyclics, Lithium
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Hematalogical
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Chronic anemia? Bleeding problems: bruise easily, hemophilia Sickle cell: trait or disease
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ASA Physical Status
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Classification based on physical condition Independent of the planned surgery Six classes (1-6) Emergency (E)
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ASA -1
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no health disturbances
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ASA -2
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Mild - mod systemic disease: HTN, DM, Obesity, Bronchitis, Smoking
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ASA -3
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Severe activity limiting systemic disturbances: cardiac pulmonary, angina previous MI, Brittle DM
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ASA - 4
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Severe systemic disturbance that is a constant threat to life: CHF, persistent angina, CRF
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ASA - 5
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Moribund patient not expected to survive 24 hours with/without surgery
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ASA - 6
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Brain dead pt for organ retrieval
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Crystalloids
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Polyionic and nearly isotonic: NS, LR (dextrose solutions generally not used) For fluid deficits replacement of up to 15% blood loss Inexpensive with little risk of allergy
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Colloids
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Protein or starch solutions (some pt have allergies) Pull fluid into the vascular space by increasing osmotic pressure Hetastarch, albumin Expensive and increased risk of allergic reaction
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Lactated Ringers
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NA 130 meq K 4 meq Ca 3 meq Cl 109 meq Lactate 28 meq Most common used fluid in anesthesia *never mix with Blood*
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0.9%
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Na 154 meq Cl 154 meq This is the ONLY solution to be used for PRBC to reduce viscosity and facilitate rapid infusion
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Colloid Solution
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Rapidly increase intravascular volume: pulls from extravascualr space May help reduce/avoid need for bld transfusion May increase tendency to bleed Dilution of clotting FX can occur with large infusion of colloids: avoid giving MORE THAN 20 ml/kg May stabilize pt while awaiting type and X-match
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Antiemetics
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Droperidol 0.625 - 2.5mg Butryrophenone r/t haloperidol Inhibits dopamenergic receptors in CTZ Cause sedation, dysphoria, extrpyramidal reactions, tar dive dyskinesia Ondansetron (Zofran) 2-4 mg SLOWLY Selective 5-HT3 receptor antagonist Works better prophylactically
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Benzodiazepines
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Produce anterograde amnesia Minimal respiratory depression Act on GABA, Limbic system, Thalamus, and Hypothalamus Anxiolytic, hypnotic, anticonvulsant, and muscle relaxant effect ROMAZICON = reversal
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Valium (Diazepam)
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Preop, standard for comparison, 1/2 life 21-37 hours: CONTRAINDICATION = glaucoma and burning with injection
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Midazolam (Versed)
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Water soluble - more rapid onset and shorter duration: greater amnesia 3-4x sedative potency: IV, PO, rectally, intranasally
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Lorazepam (Ativan)
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6-10 hour duration- Pre CABG/ventilation management
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Gastric antacids
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Neutralize/remove acid from gastric content Contains aluminum, calcium, magnesium salts
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Particulate antacids
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Maalox, Mylanta, Tums etc = may cause aspiration pna
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Non Particulate antacids
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Clear - Na Citrate, Bictra, Polycitra less likely to cause pneumonitis = unpleasant taste 15-30ml PO
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Metoclopromide (Reglan)
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10mg over 1-2 minutes Pre med with versed can make ppl feel nervous Derivative of procainamide (no LA affects) Stimulates gastric emptying Acts as an antiemetic Increases LES tone by 10-20cm H2O Effects Nervousness Does not alter gastric secretion Minimal sedation Rare extrapyramidal reactions H-2 antagonists Prophylaxis for aspiration
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Ranitidine (Zantac)
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Blocks histamine, pentagastrin, and acetylcholine induced secretions No significant effects on emptying time or volume Hepatic excretion
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Famotidine (Pepcid)
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Renal excretion
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Cimetidine (Tagamet)
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Many interactions and SE Renal/hepatic elimination Interferes with CP-450
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Replacement of hourly requirements
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First 10 kg = 4cc/kg/hr Next 10-20 kg = 2cc/kg/hr Each kg >20 = 1cc/kg/hr or 1.5cc/kg/hr adult 3cc/kg/hr child 6ml/kg/hr infant (up to 1 year) *CHEAT +40 will work for anything above 20kg
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Deficit Replacement
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Multiply maintenance rate by the NPO hours Infusion of fluid deficit 1/2 total deficit in 1st hour 1/4 total deficit in 2nd hr 1/4 in 3rd hour Try to preload 10-12ml/kg prior to induction of GA and major conduction block - helps restore deficit and prevent hypotension
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Third spacing from wound exposure
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Minor = 0-4cc/kg/hr: hernia, plastics Moderate = 4-6cc/kg/hr: appy, open choly Severe = 8-10cc/kg/hr: TKH, bowel resect, radical mastectomy
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Estimating Blood Loss: Visual
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4x4 sponges = roughly 10cc Lap pads = 150 cc Subjective - prone to error
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Estimating Blood Loss
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Changes in VS BP, HR, CVP, filling pressures, UO Analysis of Hgb/Hct Clinical appraisal : tachy, hypotension, oliguria, poor skin turgor, collapsed veins, mild/mod hypothermia, furrowed tongue, dry mucous membrane
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Morphine Sulfate
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Dose related respiratory depression Biliary tract spasm N/V, histamine release, pruritis
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Merperidine (Demerol)
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50 - 100 mg IM or 1-3 mgkg IV Treat SHIVERING in PACU 1/10 the potency of morphine Mild vagolytic and antispasmodic
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Fentanyl (Sublimaze)
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Potent analgesic = 100x as potent as morphine 50mcg/cc Rapid onset - short duration - resp depression may outlast analgesia Combined with Droperidol (Innovar) - Neuroleptanalgesia Cause chest wall rigidity
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Nasopharynx
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From bottom of nose to the end of the soft palate (connects the back of the nose to the back of the mouth)
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Oropharynx
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Opening of the mouth into the back of the throat (just behind the mouth that connects the mouth to the top of the throat)
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Hypopharnyx (Laryngopharynx)
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Sits behind on either side of the larynx (LMA - laryngeal mask airway: mask sits on the glottic opening)
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Larynx
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Connects from vocal cords down into the trachea that lvl is around C4 C5 and C6 Composed of nine cartlidges
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Unpaired cartilages
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Epiglottis Prevents aspiration by covering the glottis (opening of the larynx) during swallowing Thyroid Cricoid (The only complete circle, all the others are open towards the spine)
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Paired cartlidges
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Arytenoid Corniculate Cuneiform
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Sensory Nerves Supplying the Upper Airway
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Cranial nerve V: Trigeminal Crainial nerve IX: Glossopharyngeal Cranial nerve X: Vagus
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Division of Trigeminal Nerve
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V1: Opthalmic division (anterior ethmoidal) V2: Maxillary division (sphenopalatine) V3: Mandibular division (lingual nerve) NO INNERVATION AT THE BACK OF THE THROAT Anterior (part of tongue) think trigeminal
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IX Glossopharyngeal Nerve
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Posterior 3rd of the tongue Where the gag is located Posterior part of the throat
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X Vagus Nerve
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Sensory innervation of the larynx Parasympathetic nerve: vast innervation from eye, to neck, to uterus, to heart, to bones, to peritoneal cavity, to stomach, to carotids, etc.
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Superior laryngeal nerve (above the larynx)
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Internal branch (sensory): External branch (motor): Innervates cricothyroid muscle : dmg = unilat palsy/ paralysis = not clinically significant
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Recurrent laryngeal nerve
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Iinnervates all muscles of the airway except the cricothyroid: DMG = hoarseness and weak pronation = if damaged then vocal cords become floppy and will collapse on each other *DO NOT WANT TO DAMAGE THIS RECURRENT*
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Cricothyroid Muscle
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Innervated by the Superior Larynegeal Muscle: External branch The Cric muscle creates tension and elongation of the vocal folds
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Distance from Mentum to Hyoid bone
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With pts neck extended, measure the distance from the mentum to the hyoid bone If less than 3 fingers or 6 cm, it signals the potential for a difficult intubation Pt should be able to open mouth 6cm or 3 finger breadths
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Connection to circuit
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22 mm Outside Diameter (15 mm Inside Diameter) orifice connects to breathing circuit with right angle connector
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Components of an ETT
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The patient end of the tube is beveled to aid visualization and insertion through the vocal cords Murphy's tubes have a hole to lessen the risk of complete tube occlusion
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Intubating can be commonly associated with
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Increased heart rate, Increased BP, Increased CVP, Increased ICP, Increased intraoccular pressure
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Proper position for intubation
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Success often depends on correct positioning Texts suggest pt head should be level with anesthetist xiphoid process to prevent backstrain SNIFFING position = moderate head elevation and extension of atlanto-occipital joint Neutral with slight chin up
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Preparation for Induction and Intubation
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Routine pre-oxygenation 100% O2 3-5 min Several deep breaths Maybe okay to omit on pts who object who are free from respiratory disease and have no full stomach
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Grade 1
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A full view of the glottic opening
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Grade 2
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Posterior portion of glottic opening is visible
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Grade 3
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Only tip of epiglottis is visualized
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Grade 4
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Only soft palate visible
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Tube Placement
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Take ETT in right hand, pass tip through abducted vocal cords The tube cuff should lie in the upper trachea (mid tracheal) beyond the larynx Stylet is removed after cuff passes through cord The tube maybe advanced a little further The laryngoscope is carefully withdrawn Check the cuff against the clavicular notch
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MOV
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3-4cc Feeling the pilot balloon is not a reliable method of determining adequacy of cuff pressure Even MOV (usually at least 20mmHg) will reduce tracheal blood flow by 75% at the cuff site Further cuff inflation on induced hypotension can totally eliminate mucosal blood flow After the cuff is inflated, connected to circuit
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Endobronchial intubation
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ETT goes into right main stem bronchus d/t its less acute angle Unilateral breath sounds Unexpected hypoxia with pulse ox Inability to palpate ETT cuff in the sternal notch during cuff inflation Poor breathing bag compliance (high peak inspiratory pressure) Increaseed peak inspiratory pressure and a difference in the quality of breath sounds between the left and right lungs
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Phenylephrine nose drops (0.5% or 0.25%)
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Vasoconstrict vessels and shrink mucous membranes if not contraindicated (hypertension)
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Nasal Intubation
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If pt awake: Local anesthetic nose drops and nerve blocks can also be utilized Lubricate ETT with water soluble jelly Insert tube along the floor of the nose at an angle perpendicular to the face Gradually advance tube Perform the laryngoscopy, advance until its tip can be visualized in the oropharnyx Visualize the tube passing through cords
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Extubation Considerations
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Extubating awake pts usually associated with coughing and bucking on the ETT: Increased HR, CVP, BP, ICP, causes wound dehiscence and bleeding, often triggers bronchospasms in asthmatic patients NEVER EXTUBATE IN STAGE 2: IF EYE NOT MIDLINE (if deviate down or to side) DO NOT EXTUBATE
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Too Shallow Insertion
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Will position the cuff in the larynx Predisposes the pt to laryngeal trauma Minimal testing should include (chest auscultation, Cuff palpation, Routine capnography)
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Flexion
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Tube too far in
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Extension
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Tube too far out
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Postintubation croup
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Caused by glottic laryngeal or tracheal edema - particularly in children
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Vocal cord paralysis
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From cuff compression or other trauma Results in hoarseness and increases the risk of aspiration
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NEGATIVE PRESSURE PULMONARY EDEMA
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Large negative intrthoracic pressure generated by the struggling pt in laryngospasm can result in the development of pulmonary edema
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Anesthesia
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Total or partial loss of sensation, especially tactile, induced by disease, injury, acupuncture, or an anesthetic: The process of blocking the perception pain and other sensations
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Goals of anesthesia
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Amnesia, Analgesia, and Abolition of reflexes
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Pharmacokinetics
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What the body does to the drug (absorption, distribution, metabolism, excretion)
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Pharmacodynamics
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Study of what the drug does to the body (Effects on organs, body, and side effects)
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William Morton
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First to successfully demonstrate the use of Diethyl Ether as an anesthetic at Mass Gen
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Horace Wells
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Mass gen demonstration unsuccessful with Diethyl Ether First to think to use Diethyl Ether as an anesthetic
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John Snow
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Popularized Chloroform Many consider him the first anesthesiologist
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Alice McGraw
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The mother of anesthesia
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Agitha Hodgkins
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AANA: American Association of Nurse Anesthetists
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Spinal Ligaments
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Skin Supraspinous Interspinous Ligamentum flavum Dura Arachnoid Pia mater SILDA
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Supraspinous
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Connects tips of spinous process
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Interspinous
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Connects spinous process' horizontal surface
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Ligamentum Flavum
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Tough yellow ligament: Crunchy, scratchy sound when pierced, IMMEDIATELY BEFORE DURA
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Spinal cord
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Ends at L-1 or L2
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Dura Mater
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Tough & fibroelastic Two parts Cranial Spinal theca Ends at S2
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Arachnoid Mater
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Thin and delicate Covers brain & spinal cord Almost adherent to dura Ends at S2 Potential space Between dura and arachnoid
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Pia Mater
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Delicate Highly Vascular Clings to surface of cord and brain In subarachnoid space with CSF
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Dermatomes
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Specific region of the skin supplied by a single spinal nerve Sensory level of block
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C3,4,5
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Keep the diaphragm alive
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C6
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thumb
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C7
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middle finger
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C8
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pinkie finger
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T4
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nipple line
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T6
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xiphoid
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T8
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lower costal margin
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T10
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umbilicus
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L1
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immediately above genitals
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S1
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outer foot
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Cardiac accelerators
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Sympathetic Efferent T 1-4 High blockade -->unopposed vagal response (brady, hypotension) Prolonged brady Cardiac arrest Epinephrine
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Ventilatory Changes
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Phrenic nerve C3-5 (diaphragm) Concentration too low to block Alpha A fibers The curvature of the back helps prevent going up the neck and to the head
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Onset of SAB
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Autonomic (1st thing to go) Beta Temperature/sharp pain Alpha - delta Pain (dull) C Touch Alpha - y Pressure Alpha - Beta Motor Alpha - a Vibration Beta Proprioception Alpha - y
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Absolute Contraindications for Spinal
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Sepsis/Bacteremia Infection at puncture site Shock/severe hypovolemia Coaguopathy Therapeutic anticoagulation Increased ICP Patient refusal
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Hyperbaric
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Addition of glucose (dextrose) Usually in equal amount of LA Changes density above CSF (heavier) Settles to most dependent part of Determine by position of the patient T5-6 supine/saddle block Most commonly used Easily spread/good for abdominal surgeries
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Isobaric
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Diluting LA with preservative free NS or CSF in equal volumes In theory stays where injected regardless of pt position Good for surgery below L1 (hips)
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Hypobaric
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Addition of 6-8ml sterile water - makes density less than that of CSF (lighter) Floats to surgical area depending on patient position Good for rectal cases in jackknife position: hip cases in lateral position Rarely used b/c of unpredictability
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Lidocaine/Xylocaine
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Onset 3-5 minutes Duration 60-90 minutes Packaged 5% with 7.5% dextrose (hyperbaric) Little effect with epinephrine
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Bupivicaine/Sensorcaine
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Dose 10-15 mg Onset 5-8 minutes Duration 90 -110 minutes Packaged as 0.75% with 8.5% dextrose (hyperbaric) Little effect with epinephrine Greater sensory block than motor block
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Tetracaine/Pontocaine
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Dose 10-15mg Onset 3-6 minutes Duration 214-240 minutes Packaged 1% plain Isobaric Need to add dextrose Most flexible Most affected by epi
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1772
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N2O prepared
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Verius Cordus
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First used ether in 1540
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William Morton
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1846 First successful anesthetic
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John Snow
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First anestesiologist
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Sister Mary Bernard
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First Nurse Anesthetist
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Alice McGraw
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Mother of anesthesia 1st to publish
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Agatha Hodgins
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Founder of AANA Lakeside, Cleveland
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MAC
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Should not have loss of conciousness with loss of protective reflexes
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Spinals
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Puncture dura CSF obtained In between the Arachnoid and the pia mater
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Caudal
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Anextenion of a spinal in the sacral region
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Peripheral nerve blocks
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Brachial, Cervical plexus
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Individual nerve block
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Sciatic, intercostal
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Minimum alveolar concentration
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Decrease with hypothermia Decreases with age and is maximal at 6 months
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Minimum alveolar concentration
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Alveolar concentration of gas at which 50% of humans will not respond to noxious stimulus
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GABA
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NT associated with CNS depression
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GABA
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Sites of action are Cerebral cortex, Brain stem, Peripheral nerves, and Spinal cord
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Pharmikokinetics
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Study of what body does to the drug
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ETT
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Protects from aspiration LMA does not
question
Local anesthetic
answer
Works by blocking passage of Na ions through Na channels in nerve membrane
question
Amide = 2iis
answer
Lidocaine Bupivicaine
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Esters
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Cocaine Procaine
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Department of transportation
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Regulates medical gas cylinders
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Oxygen analyzer
answer
Best way to prevent hypoxic mixture delivery Calibrate at 21% and test at 100% with the O2 flush valve
question
Units of pressure conversion
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1atm = 1bar = 14.7psi = 101Kpa = 1033cmH2O = 760torr = 760mmHg
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O2 tank
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Max pressure 2000psi Min pressure 1000psi
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N2O
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PSI = 750 if less than 750 can measure if greater than 750 have to weigh canister to get contents 1590L
question
O2 flush valve
answer
Supplies O2 @ 35-50L/min @ 40-50 psi (whatever pipeline is)
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Check valve
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Prevents backflow to the machine
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Pressure sensor outlet shutoff valve
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N2O cannot be delivered if O2 psi <25 = cannot control if crossover of gases poccurs
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2nd stage regulator
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Reduces pressure to 12-16psi - prevents variatibilty of pipeline pressure OHMEDA
question
Oxygen ratio control monitor
answer
Prevents flow meters from delivering hypoxic mixtures
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DISS
answer
Safety system of the pipeline central supply
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PISS
answer
Saftey system for the hanger yoke
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O2 pin indexes
answer
2, 5
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CO2 pin Indexes
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3, 5
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Air
answer
Yellow
question
O2
answer
Green
question
N2O
answer
Blue
question
Different sounding alarms
answer
NOT safety mechanisms
question
Barotrauma
answer
APL Obstruction Scavenging obstruction Low outflow
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Pre-op evaluation
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Collection of info Optimization of status Care plan Decrease anxiety
question
ASA 2
answer
No health history
question
Lactated ringers
answer
4meq of K
question
Lacted ringers
answer
Most common IV fluid used in OR
question
NS 0.9%
answer
154 Na 154 Cl
question
Sccpolamine
answer
Anticholinergic that helps most with motion sickness
question
Benzos
answer
Work on GABA receptor
question
Best antacid for aspiration?
answer
Bictra
question
Valium
answer
Longest 1/2 life 21-37 hrs
question
Tagamet (Cimetidine)
answer
Many interactions with anesthesia drugs
question
Abbreviated check out
answer
Check bag Check leaks Check suction
question
Why do we monitor?
answer
Improve patient safety
question
Best monitor
answer
Pulse OX
question
A2
answer
V5 lead Anterior Axillary Line 5th ICS LAD
question
Lead II
answer
Best for P-wave monitoring Inferior wall ischemia
question
SpO2 = 90, 80, 70
answer
PaO2 = 60, 50, 40
question
ETCO2
answer
Gold standard for ETT placement 3-5 breaths
question
Which one measures oxyHgb?
answer
Infared 940 nm
question
Phase III
answer
Most physiology Best clinical reflection of alveolar CO2 tension
question
Increased ETCO2
answer
Hypoventillation Increased metabolic states Rebreathing Tourniquet release Administration of bicarb Exhausted soda lime
question
Decreased ETCO2
answer
Hypothermia Hyperventilation PE Leak in system
question
Sharp upstroke in phase III
answer
Airway resistance
question
Capnography
answer
Does not measure oxygenation Does measure ventilation, CO2, and resistance
question
Agent analyzer
answer
Tell you inspired agent compared to expired agent
question
Which temp is not used for core temp?
answer
Skin
question
Esophageal stethescope can
answer
Atrial pace Hear heart sounds and breath sounds Temp
question
V-fib
answer
Occurs when body temp 28-30 C
question
Hypothermia
answer
Arrhythmias Increased PVR Left shift of oxyHgb curve Decrease drug metabolism
question
General anesthesia
answer
Inhibits thalamic thermoregulation
question
Peripheral nerve stimulator
answer
Used to assess blockade
question
Tetany
answer
Sensitive test for Neurmuscular function Do no use on a non anesthetised pt
question
BIS 45-60
answer
Surgical anesthesia
question
Intubation
answer
ETCO2 wave forms that start high and slowly decrease
question
Slant in Phase II
answer
Obstruction (COPD, ASTHMA)
question
HCFA definition of MAC
answer
Intra-op monitoring, ancipate need for GA, adverse rxn to surgery,
question
Cardiorespiritory depression
answer
#1 cause of death in MAC
question
When can MAC be used?
answer
In any procedure when a local is likely to provide adequate anesthesia
question
Lidocaine
answer
4 mg/kg plain 7 mg/kg with epi
question
Local toxicity
answer
Tinnitus
question
Pre-seizure CNS symptoms
answer
50-100 mg STP
question
Mask conncetion
answer
22mm OD 15mm ID
question
Bagging pressure
answer
<20 mmH2O
question
Murphy's eye
answer
Decreases the risk of total occlusion of the ETT
question
ETT placement
answer
Mid tracheal beyond the larynx at least 2cm above the crycoid
question
Nasal intubation prep
answer
Affin/Pheynl dops
question
Flexion
answer
Pushes ETT in farther
question
Extension
answer
ETT comes out
question
Surgical Airway
answer
Last step in ASA difficult airway management
question
3 paired cartiladges
answer
Arytenoid Cuneiform Corniculate
question
MAC Blade
answer
Into valiculla
question
Miller blade
answer
Over epiglottis
question
Glossopharyngeal
answer
Posterior 1/3 of tongue
question
Dermatome
answer
Specific region of the skin supplied by a spinal nerve
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