Blood Anatomy Study Guide

Components of Blood
protein, erythrocytes, leukocytes, platelets, plasma
Buffy Coat
composed of leukocytes and platelets, located between erythrocytes and plasma
pH of Blood
7.35-7.45
Temperature of Blood
100.4 F
Percent of blood that are erythrocytes
45%
Percent of blood that is plasma
55%
Amount of Blood in a Healthy Male
5-6 liters
Percent of BW is Blood
8%
Percent of Plasma is Water…
90%
Plasma is made up of…
dissolved substances
Erythrocytes
red blood cells
Anemia
decrease in oxygen-carrying capacity
Polycythemia
excessive RBC’s
Leukocytes
white blood cells
Functions of Erythrocytes
carry oxygen, biconcave, hemoglobin, anucleate, few organelles
Functions of Leukocytes
nucleus and organelles, diapedesis
Diapedesis
able to move in and out of cells
Leukocytosis
high WBC count; caused by infection
Leukopenia
low WBC count; caused by drugs
Leukemia
excess, immature WBC’s
Granulocytes
neutrophils, eosinophils, basophils
Neutrophils
multi-lobed nuclei, phagocyte at infection site
Eosinophils
brick-red cytoplasmic granules, respond to allergies/parasites
Basophils
histamine-containing granules, initiate inflammation
Agranulocytes
lymphocytes, monocytes
Lymphocytes
nucleus fills cell, immune response
Megakaryocytes
ruptured multinucleate cells, needed for clotting
Platelet plug formation
collagen exposed, platelets get sticky and cling to collagen, anchored ones release chem to attract more, pile up to form plug
Coagulation
the process of blood clotting
Thrombus
clot in unbroken vessel
Embolus
clot that breaks loose, can clog elsewhere
Thrombocytopenia
platelet deficiency
Hemophilia
bleeding disorder, clotting factors missing
Shock
loss of over 30% of blood
Antigens
body sees as foreign, may be attacked by immune system
Antibodies
recognizers
ABO groups
based on presence or absence of Type A or Type B antigens